Department of Dermatology, Mater Hospital Brisbane, Queensland.
Dermatol Online J. 2020 Oct 15;26(10):13030/qt0s39g4tt.
Cutaneous collagenous vasculopathy (CCV) is a rare idiopathic microangiopathy affecting superficial dermal blood vessels. It is characterized by asymptomatic, disseminated, telangiectatic macules that typically involve the extremities. We report the case of a 58-year-old woman who presented with widespread telangiectasias of three years' duration on the upper extremities and abdomen. Cutaneous collagenous vasculopathy may be underdiagnosed as it is often mistaken for disorders that are morphologically very similar, including generalized essential telangiectasia, hereditary hemorrhagic telangiectasia, and pigmented purpuric dermatosis. The diagnosis of CCV is made histologically and findings feature dilated superficial dermal vessels with thickened walls containing periodic acid-Schiff-positive eosinophilic hyaline material. Effective treatment options for CCV have yet to be established and given its benign disease course, treatment may not be necessary. Pulsed dye laser can be offered to patients for cosmetic improvement but the extent of the disease makes complete lesion clearance challenging in most cases. Given the lesions were asymptomatic our patient declined all offered treatment modalities.
皮肤胶原性血管病 (CCV) 是一种罕见的特发性微血管病,影响真皮浅层血管。其特征为无症状、播散性、毛细血管扩张性斑疹,通常累及四肢。我们报告了一例 58 岁女性病例,其上肢和腹部广泛出现毛细血管扩张,病史达 3 年。由于 CCV 常被误诊为形态非常相似的疾病,包括全身性特发性毛细血管扩张症、遗传性出血性毛细血管扩张症和色素性紫癜性皮肤病,因此可能存在漏诊。CCV 的诊断是组织学上的,其特征为扩张的真皮浅层血管,壁增厚,含有 PAS 阳性嗜酸性透明物质。CCV 的有效治疗方法尚未确定,鉴于其良性疾病过程,可能不需要治疗。脉冲染料激光可用于改善美容,但由于疾病范围广泛,在大多数情况下难以完全清除病变。鉴于病变无症状,我们的患者拒绝了所有提供的治疗方法。