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卡彭蒂埃-爱德华兹经典和生理性二尖瓣成形环在退行性二尖瓣疾病修复中的应用:一项回顾性研究

The Carpentier-Edwards Classic and Physio Annuloplasty Rings in Repair of Degenerative Mitral Valve Disease: A Retrospective Study.

作者信息

Sidiki Abubakari I, Faybushevich Alexandr G, Lishchuk Alexandr N, Koltunov Alexandr N, Roshchina Ekaterina A

机构信息

Department of Cardiothoracic Surgery, People's Friendship University of Russia (RUDN-University), Moscow, Russia.

Department of Surgery, People's Friendship University of Russia (RUDN-University), Moscow, Russia.

出版信息

J Saudi Heart Assoc. 2020 May 20;32(2):224-232. doi: 10.37616/2212-5043.1027. eCollection 2020.

Abstract

BACKGROUND

Physio ring (SR) is considered an improved version of the Classic rigid ring (RR). Today, SR is more widely used in mitral valve (MV) repair. We sought to compare the long-term outcomes of repair with RR and SR in degenerative mitral valve disease.

METHODS

In a computerized registry of our institution, 306 patients had MV repair with either RR (139 patients) or SR (167 patients) ring between 2005 and 2015. Fifteen of them had concomitant tricuspid valve repair. Ninety-two (30.1%) had Barlow's disease and 214 (69.9%) had fibroelastic deficiency. The patients had similar demographic and echocardiographic characteristics.

RESULTS

There were 4 (1.3%) operative mortalities. Mean follow-up time was 107.4 ± 13.2 months. Left ventricular end diastolic and end systolic diameters significantly improved in both groups but not between groups. Survival at 10 years was 84.6% (93.1% in RR and 91.5% in SR; p = 0.177) and 10-year freedom from recurrent MR ≥ 2+ was 74.5% (88.2% in RR and 86.3% in SR; p = 0.110). Reoperations for repair failure were 8 in RR and 6 in SR. By Cox regression analysis, Barlow's disease and preoperative MR = 4 were predictors of repair failure. Old age (≥70 years), NYHA functional class IV and pulmonary artery systolic pressure (≥40 mmHg) were predictors of poor survival by univariate analysis.

CONCLUSION

Long-term outcomes of repair for degenerative MV disease with the Classic and Physio rings are comparable. We also reiterate the importance of large size annuloplasty rings for Barlow's disease to avoid the incidence left ventricular outflow obstruction.

摘要

背景

生理环(SR)被认为是经典刚性环(RR)的改进版本。如今,SR在二尖瓣(MV)修复中应用更为广泛。我们旨在比较RR和SR用于退行性二尖瓣疾病修复的长期疗效。

方法

在我们机构的计算机化登记系统中,2005年至2015年间,306例患者接受了RR(139例患者)或SR(167例患者)环的MV修复。其中15例同时进行了三尖瓣修复。92例(30.1%)患有巴洛病,214例(69.9%)患有纤维弹性组织缺乏症。患者的人口统计学和超声心动图特征相似。

结果

有4例(1.3%)手术死亡。平均随访时间为107.4±13.2个月。两组的左心室舒张末期和收缩末期直径均显著改善,但组间无差异。10年生存率为84.6%(RR组为93.1%,SR组为91.5%;p = 0.177),10年无复发性中重度二尖瓣反流(MR≥2+)的比例为74.5%(RR组为88.2%,SR组为86.3%;p = 0.110)。RR组因修复失败再次手术的有8例,SR组有6例。通过Cox回归分析,巴洛病和术前MR = 4是修复失败的预测因素。单因素分析显示,高龄(≥70岁)、纽约心脏协会(NYHA)功能分级IV级和肺动脉收缩压(≥40 mmHg)是生存不良的预测因素。

结论

经典环和生理环用于退行性MV疾病修复的长期疗效相当。我们还重申了大尺寸瓣环成形环对巴洛病的重要性,以避免左心室流出道梗阻的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a366/7640569/a816cfab24a4/sha-32-02-224f1.jpg

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