Dreyfus M, Jonard M, Rigouzzo A, Weber P
Service gynécologie obstétrique et médecine de la reproduction, CHU de Caen, université de Caen, avenue Côte-de-Nacre, 14033 Caen cedex 09, France.
Service de réanimation polyvalente pôle de soins critiques, hôpital de Lens, 99, route de la Bassée, 62307 Lens, France.
Gynecol Obstet Fertil Senol. 2021 Jan;49(1):79-82. doi: 10.1016/j.gofs.2020.11.014. Epub 2020 Nov 5.
Between 2013 and 2015, six maternal deaths were due to hypertensive disorders. During this period, the maternal mortality ratio was 0.2/100,000 live births. Hypertensive disorders were responsible for 2% of maternal deaths in France and for 5% of direct maternal mortality. All these deaths happened after the delivery. Mode of delivery was a cesarean section when the hypertensive complication started before the delivery (4/6; 67%). Three had DIC during the immediate post-partum. Five women were under 35 years old. Only one had a BMI over 30. Four out of six patients were primiparous. One woman was Afro-Caribbean. Medical care was estimated non-optimal in 100% of the cases. In three cases, it was prenatal care and in three cases it was obstetrical care during delivery; anesthesia and intensive care were suboptimal in five cases. Eighty percent of these deaths seemed to be preventable. The main causes of suboptimal management were inappropriate or insufficient obstetrical and/or anesthetic treatments, and delayed optimal treatment. The analysis of these maternal deaths offers the opportunity to stress major points to optimize medical management in case of hypertensive disorders during pregnancy such as management of eclampsia (use of magnesium sulfate) or recognition of DIC when HELLP syndrome is diagnosed.
2013年至2015年间,有6例孕产妇死亡归因于高血压疾病。在此期间,孕产妇死亡率为0.2/10万活产。高血压疾病导致法国2%的孕产妇死亡,占孕产妇直接死亡的5%。所有这些死亡均发生在分娩后。当高血压并发症在分娩前开始时,分娩方式为剖宫产(4/6;67%)。3例在产后立即发生弥散性血管内凝血。5名女性年龄在35岁以下。只有1名女性的体重指数超过30。6例患者中有4例为初产妇。1名女性是非洲裔加勒比人。估计100%的病例医疗护理都不理想。3例是产前护理问题,3例是分娩期间的产科护理问题;5例麻醉和重症监护不理想。这些死亡中80%似乎是可以预防的。管理欠佳的主要原因是产科和/或麻醉治疗不当或不足,以及最佳治疗延迟。对这些孕产妇死亡病例的分析提供了一个机会,以强调在孕期高血压疾病情况下优化医疗管理的要点,如子痫的管理(使用硫酸镁)或在诊断为HELLP综合征时识别弥散性血管内凝血。