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越南河内个人护理产品和室内灰尘中的防腐剂:时间趋势、排放源以及通过灰尘摄入的非饮食暴露。

Parabens in personal care products and indoor dust from Hanoi, Vietnam: Temporal trends, emission sources, and non-dietary exposure through dust ingestion.

机构信息

Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, 19 Le Thanh Tong, Hanoi 10000, Viet Nam.

Institute of Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi 10000, Viet Nam.

出版信息

Sci Total Environ. 2021 Mar 20;761:143274. doi: 10.1016/j.scitotenv.2020.143274. Epub 2020 Oct 28.

Abstract

The occurrence of seven typical parabens was investigated in several types of personal care products (PCPs) sold at supermarkets and in indoor dust samples collected from houses, laboratories, and medical stores in Hanoi, Vietnam. Parabens were frequently detected in PCPs regardless of the paraben indication in their ingredient labels. However, concentrations of parabens in labeled products (median 3280; range 1370-5610 μg/g) were much higher than those found in non-labeled products (69.4; not detected - 356 μg/g). Parabens were also measured in indoor dust samples of this study at elevated concentrations, ranging from not detected to 1650 (median 286 ng/g). Levels of parabens in the indoor dust samples collected in 2019 decreased in the order: house > medical store > laboratory dust, however, the difference was not statistically significant. Interestingly, levels of parabens in Vietnamese house dust exhibited an increasing trend over time, for example, mean/median concentrations of parabens in house dust samples collected in 2014, 2017, and 2019 were 245/205, 310/264, and 505/379 ng/g, respectively. Methylparaben was found at the highest frequency and concentrations in both PCPs and indoor dust samples. Mean exposure doses of total parabens through dust ingestion were estimated to be 2.02, 1.61, 0.968, 0.504, and 0.192 ng/kg-bw/d for infants, toddlers, children, teenagers, and adults, respectively. Further studies on the distribution, emission behavior, potential sources, and negative impacts of parabens in different environmental media in Vietnam are needed.

摘要

本研究调查了在越南河内的超市销售的个人护理产品(PCP)和从房屋、实验室和药店采集的室内灰尘样本中七种典型的防腐剂的存在情况。无论成分标签中是否有防腐剂,PCP 中都经常检测到防腐剂。然而,标签产品中的防腐剂浓度(中位数 3280;范围 1370-5610μg/g)远高于非标签产品(69.4;未检出-356μg/g)。本研究还在室内灰尘样本中检测到了浓度较高的防腐剂,范围从未检出到 1650(中位数 286ng/g)。2019 年采集的室内灰尘样本中的防腐剂水平按以下顺序降低:房屋>药店>实验室灰尘,但差异无统计学意义。有趣的是,越南家庭灰尘中的防腐剂水平呈上升趋势,例如,2014 年、2017 年和 2019 年采集的家庭灰尘样本中防腐剂的平均/中位数浓度分别为 245/205、310/264 和 505/379ng/g。在 PCP 和室内灰尘样本中,均发现了最高频率和浓度的甲基对羟基苯甲酸酯。通过灰尘摄入估计的总防腐剂的平均暴露剂量分别为婴儿 2.02、幼儿 1.61、儿童 0.968、青少年 0.504 和成人 0.192ng/kg-bw/d。需要进一步研究防腐剂在越南不同环境介质中的分布、排放行为、潜在来源和负面影响。

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