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使用多血管移植物的机器人辅助肾移植的可行性和功能结局:与倾向匹配的当代开放性肾移植队列的比较。

Feasibility and Functional Outcome of Robotic Assisted Kidney Transplantation Using Grafts With Multiple Vessels: Comparison to Propensity Matched Contemporary Open Kidney Transplants Cohort.

作者信息

Nataraj Sachin Arakere, Zafar Feroz Amir, Ghosh Prasun, Ahlawat Rajesh

机构信息

Institute of Urology and Robotic Surgery Medanta, The Medicity Gurgaon, Gurgaon, India.

出版信息

Front Surg. 2020 Aug 25;7:51. doi: 10.3389/fsurg.2020.00051. eCollection 2020.

Abstract

The aim of the study was to report the perioperative and functional results of Robotic assisted kidney transplantation (RAKT) in Grafts with multiple vessels (GMVs) and compare it to the results of Open kidney transplantation (OKT) with GMVs. Patients undergoing RAKT from living donors using GMVs were reviewed from prospectively collected RAKT database at our institution between March 2013 and March 2018. Patient undergoing Open kidney transplantation (OKT) using GMVs served as controls. bench surgical reconstruction of GMVs was done according to specific anatomy. Propensity score matching was used to balance the sample size in the two groups. Of 153 RAKT and OKT procedures, 86 cases were eligible for propensity score matching for the statistically significant variables (standardized difference >0.10) and 43 procedures were assigned to each group. Median anastomoses, total and cold ischemia and rewarming times did not differ significantly between the RAKT and OKT groups. In comparison with OKT in GMVs we found that RAKT with GMVs had less pain score on post op 2nd day ( = 0.03). There was also a significant difference in mean analgesic requirement ( = 0.02), hospital stay ( = 0.05) and incision length ( = 0.04). Most of the major, minor surgical, and medical postoperative complications were comparable between the two groups except for wound related events ( = 0.002). Multiplicity of renal vessels in RAKT does not adversely affect patient or graft survival compared with the OKT. Satisfactory functional outcome can be achieved by RAKT similar to OKT in GMVs. RAKT seems to have advantage over OKT in that it is less invasive and has the potential to cause fewer low grade complications. Small sample size and short follow-up are the main limitations of the study.

摘要

本研究的目的是报告机器人辅助肾移植(RAKT)在多支血管移植物(GMV)中的围手术期及功能结果,并将其与开放性肾移植(OKT)在GMV中的结果进行比较。对2013年3月至2018年3月期间在本机构前瞻性收集的RAKT数据库中接受活体供体GMV的RAKT患者进行了回顾。接受开放性肾移植(OKT)使用GMV的患者作为对照。根据特定解剖结构对GMV进行体外手术重建。采用倾向评分匹配法平衡两组样本量。在153例RAKT和OKT手术中,86例符合倾向评分匹配的统计学显著变量(标准化差异>0.10),每组分配43例手术。RAKT组和OKT组之间的中位吻合时间、总缺血和冷缺血及复温时间差异无统计学意义。与GMV中的OKT相比,我们发现GMV的RAKT在术后第2天疼痛评分更低(P = 0.03)。平均镇痛需求(P = 0.02)、住院时间(P = 0.05)和切口长度(P = 0.04)也存在显著差异。除伤口相关事件外(P = 0.002),两组的大多数主要、次要手术及术后医疗并发症相当。与OKT相比,RAKT中肾血管的多样性对患者或移植物存活无不利影响。RAKT在GMV中可实现与OKT相似的满意功能结果。RAKT似乎比OKT更具优势,因为它侵入性更小,且可能导致更少的低级别并发症。小样本量和短随访是本研究的主要局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1fb/7477351/4ede1d441f63/fsurg-07-00051-g0001.jpg

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