Himmelhoch J M
Department of Psychiatry, University of Pittsburgh, School of Medicine, Western Psychiatric Institute and Clinic, PA 15213.
J Clin Psychiatry. 1987 Dec;48 Suppl:44-54.
Epidemiologic data have identified risk factors, such as major depressive illness and sedative/alcohol addiction, that can help the clinician detect potentially suicidal persons. Evidence of subtle differences in the pattern of suicidality in bipolar and unipolar depressive illnesses has emerged. Suicide occurs early in unipolar episodes and intensifies along with increasing agitation and worsening melancholic symptoms. In bipolar depressive episodes, suicidality becomes an issue late in the course of a single episode, and illness severity and lethality are progressively aggravated by each affective relapse. Safe, effective treatment for suicide patients is the responsibility of the individual clinician and depends on neuropsychiatric variables, proper therapy, and direct and honest communication between patient and clinician. Adamant avoidance of division of primary clinical responsibility among cooperating specialists and clinician obstinancy when dealing with third parties can help prevent suicides. Early identification of psychosis, sedativism and subtle organicity are imperative. Pharmacotherapy usually equates to the fastest acting, most effective antidepressant drug, but some patients require electroconvulsive therapy to reduce suicidality. Involvement is the essence of psychotherapy in suicide management.
流行病学数据已确定了一些风险因素,如重度抑郁症和镇静剂/酒精成瘾,这些因素可帮助临床医生识别潜在的自杀者。双相情感障碍和单相抑郁症患者自杀模式的细微差异已有相关证据。自杀在单相发作早期出现,并随着激越加剧和抑郁症状恶化而增强。在双相抑郁发作中,自杀倾向在单次发作后期才成为问题,且每次情感复发都会使病情严重程度和致死率逐渐加重。对自杀患者进行安全、有效的治疗是临床医生个人的责任,这取决于神经精神变量、适当的治疗方法以及患者与临床医生之间直接而坦诚的沟通。坚决避免合作专家之间对主要临床责任的推诿,以及临床医生在与第三方打交道时的固执态度,有助于预防自杀。早期识别精神病、镇静状态和细微的器质性病变至关重要。药物治疗通常等同于起效最快、最有效的抗抑郁药物,但有些患者需要接受电休克治疗以降低自杀倾向。参与是自杀管理中心理治疗的关键所在。