Department of Environmental Sciences, Rutgers, The State University of New Jersey, 14 College Farm Road, New Brunswick, NJ, 08901, USA.
J Expo Sci Environ Epidemiol. 2021 Nov;31(6):1032-1046. doi: 10.1038/s41370-020-00278-1. Epub 2020 Nov 18.
Cosmetic powders contain numerous components, including titanium dioxide (TiO), which is classified as possibly carcinogenic to humans (Group 2B). However, little is known about potential inhalation exposures to particles that are released during cosmetic powder applications.
We realistically simulated the application of five different eyebrow powders using a mannequin and then determined concentrations of total suspended particles (TSP), PM, and PM fractions of particles that would be inhaled during powder application. We determined the size and shape of particles in the original powders and released particles, as well as their TiO concentrations and Ti content of individual particles.
The application of eyebrow powders resulted in the release and inhalation of airborne particles at concentrations ranging from 21.2 to 277.3 µg/m, depending on the particle fraction and the powder. The concentrations of TiO in PM and PM samples reached 2.7 µg/m and 9.3 µg/m, respectively. The concentration of TiO in airborne particle fractions was proportional to the presence of TiO in the bulk powder.
The application of eyebrow powders results in user exposures to respirable PM and PM particles, including those containing TiO. This information should be of interest to stakeholders concerned about inhalation exposure to TiO.
化妆品粉末包含多种成分,其中包括被归类为可能对人类致癌(第 2B 组)的二氧化钛(TiO)。然而,对于在化妆品粉末应用过程中释放的颗粒的潜在吸入暴露,人们知之甚少。
我们使用人体模型真实模拟了五种不同眉粉的应用,然后确定了在粉末应用过程中吸入的总悬浮颗粒物(TSP)、PM 和 PM 颗粒分数的浓度。我们确定了原始粉末和释放的颗粒中的颗粒的大小和形状,以及它们的 TiO 浓度和单个颗粒的 Ti 含量。
根据颗粒分数和粉末的不同,眉粉的应用导致释放和吸入空气中的颗粒浓度范围为 21.2 至 277.3 µg/m。PM 和 PM 样品中的 TiO 浓度分别达到 2.7 µg/m 和 9.3 µg/m。空气中颗粒分数中的 TiO 浓度与散装粉末中 TiO 的存在成正比。
使用眉粉会导致使用者接触到可吸入的 PM 和 PM 颗粒,其中包括含有 TiO 的颗粒。对于那些关注 TiO 吸入暴露的利益相关者来说,这些信息应该是有意义的。