Vedel Isabelle, Sheets Debra, McAiney Carrie, Clare Linda, Brodaty Henry, Mann James, Anderson Nicole, Liu-Ambrose Teresa, Rojas-Rozo Laura, Loftus Lynn, Gauthier Serge, Sivananthan Saskia
McGill University Montreal Quebec Canada.
School of Nursing University of Victoria Victoria British Columbia Canada.
Alzheimers Dement (N Y). 2020 Nov 11;6(1):e12086. doi: 10.1002/trc2.12086. eCollection 2020.
Current pharmacological therapies for dementia have limited efficacy. Thus it is important to provide recommendations on individual and community-based psychosocial and non-pharmacological interventions for persons living with dementia (PLWDs) and their caregivers.
Phase 1: A systematic review for developing recommendations on psychosocial and non-pharmacological interventions at the individual and community level for PLWDs and their caregivers. Phase 2: Rating of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines. Phase 3: Delphi process (>50 dementia experts) for approving recommendations by the 5 Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD5).
The CCCDTD5 approved the following recommendations: Exercise (1B) and group cognitive stimulation for PLWDs (2B), psychosocial and psychoeducational interventions for caregivers (2C), development of dementia friendly organization and communities (2C), and case management for PLWDs (2B).
The CCCDTD5 provides for the first time, evidence-based recommendations on psychosocial and non-pharmacological interventions for PLWDs and their caregivers that can inform evidence-based policies for PLWDs in Canada.
目前用于治疗痴呆症的药物疗法疗效有限。因此,为痴呆症患者(PLWDs)及其护理人员提供基于个体和社区的心理社会及非药物干预建议非常重要。
第一阶段:进行系统综述,以制定关于针对PLWDs及其护理人员在个体和社区层面的心理社会及非药物干预的建议。第二阶段:使用推荐分级评估、制定和评价(GRADE)指南对建议进行评级。第三阶段:通过加拿大第五届痴呆症诊断与治疗共识会议(CCCDTD5)的德尔菲法(>50名痴呆症专家)批准建议。
CCCDTD5批准了以下建议:为PLWDs进行锻炼(1B)和团体认知刺激(2B),为护理人员提供心理社会和心理教育干预(2C),发展对痴呆症友好的组织和社区(2C),以及为PLWDs提供病例管理(2B)。
CCCDTD5首次提供了关于针对PLWDs及其护理人员的心理社会及非药物干预的循证建议,可为加拿大针对PLWDs的循证政策提供参考。