Kothiwale Shaila, Ajbani Jyoti
Department of Periodontics, KLEs V. K. Institute of Dental Sciences, KAHER, Belagavi, Karnataka, 590010, India.
Cell Tissue Bank. 2021 Sep;22(3):389-398. doi: 10.1007/s10561-020-09884-7. Epub 2020 Nov 24.
Width of attached gingiva plays an important role in maintaining periodontal health, provides stabilization of the gingival margin against frictional forces and aids in dissipating physiological forces exerted by the muscular fibers of the alveolar mucosa on the gingival tissues. Inadequate width of attached gingiva leads to attachment loss, soft tissue recession, and impedes oral hygiene measures. Hence, procedures using autografts and allografts have been proposed to augment the attached gingiva. Allografts like chorionic membrane (CM) are known to enhance release of growth factors, promote neovascularization, healing and enhance biotype. To assess the efficacy of CM in increasing the width of attached gingiva, vestibular depth and gingival thickness. Fifteen patients with inadequate attached gingival width were included in the study. Patients were randomly allocated to each group: Control group, CM group and CM + platelet rich fibrin (PRF) group. Attached gingiva width, vestibular depth, and gingival thickness were measured at baseline and 4 weeks post procedure. The control, CM and CM + PRF groups showed an increase in all parameters from baseline to 4 weeks. The increase in the attached gingiva (p = 0.042) width, vestibular depth (p = 0.043) and gingival thickness (p = 0.034) were statistically significant at 4 weeks for CM group and CM + PRF group respectively. The CM + PRF group showed better results compared to other groups. CM and PRF can be effectively incorporated to increase the width of attached gingiva and depth of vestibule.
附着龈宽度在维持牙周健康方面起着重要作用,可稳定龈缘以抵抗摩擦力,并有助于消散牙槽黏膜肌纤维对牙龈组织施加的生理力。附着龈宽度不足会导致附着丧失、软组织退缩,并妨碍口腔卫生措施。因此,已提出使用自体移植和异体移植的方法来增加附着龈。已知异体移植物如绒毛膜(CM)可促进生长因子释放、促进新血管形成、愈合并改善生物型。为评估CM增加附着龈宽度、前庭深度和牙龈厚度的疗效。15例附着龈宽度不足的患者纳入本研究。患者被随机分配到每组:对照组、CM组和CM +富血小板纤维蛋白(PRF)组。在基线和术后4周测量附着龈宽度、前庭深度和牙龈厚度。对照组、CM组和CM + PRF组从基线到4周所有参数均增加。CM组和CM + PRF组在4周时附着龈宽度(p = 0.042)、前庭深度(p = 0.043)和牙龈厚度(p = 0.034)的增加具有统计学意义。CM + PRF组与其他组相比显示出更好的结果。CM和PRF可有效联合使用以增加附着龈宽度和前庭深度。