人乳头瘤病毒基因分型作为宫颈癌预防工具：从商用的人乳头瘤病毒DNA检测到新一代测序
Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human papillomavirus DNA test to next-generation sequencing.
作者信息
Dias Tauana Christina, Longatto-Filho Adhemar, Campanella Nathalia C
机构信息
Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo, Brazil.
Life & Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.
出版信息
Future Sci OA. 2020 Jul 30;6(9):FSO603. doi: 10.2144/fsoa-2019-0159.
Abstract
The biological importance of human papillomavirus (HPV) in the field of medicine - related to cervical carcinogenesis - has been extensively reported in the last decades. For the first time, a direct correlation between cause and effect to explain a cancer development was completely achieved in medical research. Consequently, the Nobel Prize was awarded to HZ Hausen in 2008 for his efforts to understand the effects of persistent infection of oncogenic types of HPV and malignancy transformation. The aim of the present review was to summarize the principal elements of HPV characteristics and their importance in oncology.
摘要
在过去几十年中，人乳头瘤病毒（HPV）在与宫颈癌发生相关的医学领域中的生物学重要性已得到广泛报道。在医学研究中，首次完全实现了因果之间的直接关联以解释癌症的发展。因此，HZ豪森因努力了解致癌型HPV持续感染的影响和恶性转化而于2008年被授予诺贝尔奖。本综述的目的是总结HPV特征的主要内容及其在肿瘤学中的重要性。
相似文献
1
Human papillomavirus genotyping as a tool for cervical cancer prevention: from commercially available human papillomavirus DNA test to next-generation sequencing.人乳头瘤病毒基因分型作为宫颈癌预防工具：从商用的人乳头瘤病毒DNA检测到新一代测序
Future Sci OA. 2020 Jul 30;6(9):FSO603. doi: 10.2144/fsoa-2019-0159.
2
Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins.高危型人乳头瘤病毒致宫颈癌的分子机制：E6和E7癌蛋白的新功能
Rev Med Virol. 2009 Mar;19(2):97-113. doi: 10.1002/rmv.605.
3
[Molecular basis of cervical carcinogenesis by high-risk human papillomaviruses].[高危型人乳头瘤病毒致宫颈癌的分子机制]
Uirusu. 2008 Dec;58(2):141-54. doi: 10.2222/jsv.58.141.
4
Genetic variability in E6, E7 and L1 genes of Human Papillomavirus 62 and its prevalence in Mexico.人乳头瘤病毒62型E6、E7和L1基因的遗传变异性及其在墨西哥的流行情况。
Infect Agent Cancer. 2017 Mar 4;12:15. doi: 10.1186/s13027-017-0125-x. eCollection 2017.
5
Establishment and Application of a Method for High-Risk Human Papillomavirus Genotyping in Cervical Cancer Tissue.宫颈癌组织中高危型人乳头瘤病毒基因分型方法的建立与应用
Clin Lab. 2016;62(6):1075-85. doi: 10.7754/clin.lab.2015.151007.
6
Human papillomavirus genotype distribution and E6/E7 oncogene expression in Turkish women with cervical cytological findings.土耳其宫颈细胞学检查结果异常女性的人乳头瘤病毒基因型分布及E6/E7癌基因表达
Asian Pac J Cancer Prev. 2014;15(9):3997-4003. doi: 10.7314/apjcp.2014.15.9.3997.
7
Eight-type human papillomavirus E6/E7 oncoprotein detection as a novel and promising triage strategy for managing HPV-positive women.八型人乳头瘤病毒 E6/E7 癌蛋白检测作为一种新型且有前途的策略，用于管理 HPV 阳性女性。
Int J Cancer. 2019 Jan 1;144(1):34-42. doi: 10.1002/ijc.31633. Epub 2018 Oct 26.
8
Quantitation of human papillomavirus 16 E6 and E7 DNA and RNA in residual material from ThinPrep Papanicolaou tests using real-time polymerase chain reaction analysis.使用实时聚合酶链反应分析对ThinPrep巴氏试验剩余材料中的人乳头瘤病毒16 E6和E7 DNA及RNA进行定量分析。
Cancer. 2002 Apr 15;94(8):2199-210. doi: 10.1002/cncr.10439.
9
Next generation sequencing for human papillomavirus genotyping.下一代测序技术用于人类乳头瘤病毒基因分型。
J Clin Virol. 2013 Oct;58(2):437-42. doi: 10.1016/j.jcv.2013.07.013. Epub 2013 Aug 8.
10
Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region.通过E6/E7区域的下一代深度测序对致癌性人乳头瘤病毒的型内变体进行特征分析
Viruses. 2016 Mar 14;8(3):79. doi: 10.3390/v8030079.
本文引用的文献
1
Cervical cancer screening program based on primary DNA-HPV testing in a Brazilian city: a cost-effectiveness study protocol.基于巴西某城市 HPV 初筛的宫颈癌筛查项目：成本效果研究方案
BMC Public Health. 2020 Apr 28;20(1):576. doi: 10.1186/s12889-020-08688-4.
2
Carcinogenesis Associated with Human Papillomavirus Infection. Mechanisms and Potential for Immunotherapy.与人类乳头瘤病毒感染相关的癌症发生。机制和免疫治疗的潜力。
Biochemistry (Mosc). 2019 Jul;84(7):782-799. doi: 10.1134/S0006297919070095.
3
Targeted juglone blocks the invasion and metastasis of HPV-positive cervical cancer cells.靶向胡桃醌阻断 HPV 阳性宫颈癌的侵袭和转移。
J Pharmacol Sci. 2019 Jul;140(3):211-217. doi: 10.1016/j.jphs.2019.06.013. Epub 2019 Aug 10.
4
The advent of human papillomavirus detection for cervical screening.人乳头瘤病毒检测在宫颈癌筛查中的应用。
Curr Opin Obstet Gynecol. 2019 Oct;31(5):333-339. doi: 10.1097/GCO.0000000000000542.
5
Identification of human papillomavirus type 16 variants circulating in the Calabria region by sequencing and phylogenetic analysis of HPV16 from cervical smears.通过对宫颈涂片 HPV16 进行测序和系统进化分析，鉴定卡拉布里亚地区流行的人乳头瘤病毒 16 型变异体。
Infect Genet Evol. 2019 Mar;68:185-193. doi: 10.1016/j.meegid.2018.12.024. Epub 2018 Dec 20.
6
The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium.Valgent4 方案：对使用 SurePath 介质采集的宫颈样本进行 11 种 HPV 检测与基因分型的稳健分析和临床验证。
J Clin Virol. 2018 Nov;108:64-71. doi: 10.1016/j.jcv.2018.09.012. Epub 2018 Sep 17.
7
High-Risk Human Papillomaviral Oncogenes E6 and E7 Target Key Cellular Pathways to Achieve Oncogenesis.高危型人乳头瘤病毒致癌基因 E6 和 E7 靶向关键细胞通路以实现癌变。
Int J Mol Sci. 2018 Jun 8;19(6):1706. doi: 10.3390/ijms19061706.
8
Mechanisms by which HPV Induces a Replication Competent Environment in Differentiating Keratinocytes.人乳头瘤病毒在分化角质形成细胞中诱导复制活性环境的机制。
Viruses. 2017 Sep 19;9(9):261. doi: 10.3390/v9090261.
9
The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets.HPV E6/E7 致癌基因：病毒致癌的关键因素和治疗靶点。
Trends Microbiol. 2018 Feb;26(2):158-168. doi: 10.1016/j.tim.2017.07.007. Epub 2017 Aug 17.
10
The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review.人乳头瘤病毒复制周期及其与癌症进展的关联：全面综述
Clin Sci (Lond). 2017 Aug 10;131(17):2201-2221. doi: 10.1042/CS20160786. Print 2017 Sep 1.
Zotero 插件