β-内酰胺类抗生素过敏记录与手术预防性应用抗生素的关联：一项全国性住院患者的横断面研究。
Association of β-Lactam Allergy Documentation and Prophylactic Antibiotic Use in Surgery: A National Cross-Sectional Study of Hospitalized Patients.
机构信息
Northwestern Memorial Hospital, Department of Pharmacy, Chicago, Illinois, USA.
Department of Pharmacy Practice, College of Pharmacy, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA.
出版信息
Clin Infect Dis. 2021 Jun 1;72(11):e872-e875. doi: 10.1093/cid/ciaa1762.
Alternative antibiotics for surgical prophylaxis are associated with increased adverse events and surgical site infection compared to cefazolin. In a sample of perioperative inpatients from 100 hospitals in the United States, cefazolin was 9-fold less likely to be used in patients with a documented β-lactam allergy whereas clindamycin was 45-fold more likely.
与头孢唑林相比，用于手术预防的替代抗生素与不良事件和手术部位感染的发生率增加相关。在美国 100 家医院的围手术期住院患者样本中，有记录的β-内酰胺类过敏患者使用头孢唑林的可能性低 9 倍，而克林霉素的可能性高 45 倍。
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