用于灭活新型冠状病毒的低温大气等离子体
Cold atmospheric plasma for SARS-CoV-2 inactivation.
作者信息
Chen Zhitong, Garcia Gustavo, Arumugaswami Vaithilingaraja, Wirz Richard E
机构信息
Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, California 90095, USA.
Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California 90095, USA.
出版信息
Phys Fluids (1994). 2020 Nov 1;32(11):111702. doi: 10.1063/5.0031332.
Syndrome coronavirus 2 (SARS-CoV-2) infectious virions are viable on various surfaces (e.g., plastic, metals, and cardboard) for several hours. This presents a transmission cycle for human infection that can be broken by developing new inactivation approaches. We employed an efficient cold atmospheric plasma (CAP) with argon feed gas to inactivate SARS-CoV-2 on various surfaces including plastic, metal, cardboard, basketball composite leather, football leather, and baseball leather. These results demonstrate the great potential of CAP as a safe and effective means to prevent virus transmission and infections for a wide range of surfaces that experience frequent human contact. Since this is the first-ever demonstration of cold plasma inactivation of SARS-CoV-2, it is a significant milestone in the prevention and treatment of coronavirus disease 2019 (COVID-19) and presents a new opportunity for the scientific, engineering, and medical communities.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染性病毒粒子在各种表面（如塑料、金属和纸板）上可存活数小时。这呈现了一个人类感染传播循环，可通过开发新的灭活方法来打破。我们采用了一种以氩气为进料气体的高效冷大气等离子体（CAP）来灭活包括塑料、金属、纸板、篮球合成皮革、足球皮革和棒球皮革在内的各种表面上的SARS-CoV-2。这些结果证明了CAP作为一种安全有效的手段在预防广泛频繁接触人类的表面上的病毒传播和感染方面具有巨大潜力。由于这是首次证明冷等离子体对SARS-CoV-2的灭活作用，它是2019冠状病毒病（COVID-19）预防和治疗中的一个重要里程碑，并为科学界、工程界和医学界带来了新机遇。
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