Division of Head and Neck department, Otorhinolaryngology unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Laryngoscope. 2021 Jul;131(7):1683-1692. doi: 10.1002/lary.29297. Epub 2020 Nov 28.
OBJECTIVES/HYPOTHESIS: To estimate the impact of optical techniques on prevention of post-operative hypocalcemia and hypoparathyroidism after total thyroidectomy.
Systematic review and meta-analysis.
A literature search was conducted in Pubmed, EMBASE, SCOPUS, and Cochrane databases. The main inclusion criteria for eligible articles for meta-analysis were patients with benign or malignant thyroid pathologies who underwent total thyroidectomy, utilization of optical techniques to support PGs preservation, the availability of calcium and/or PTH levels. The primary outcome was to evaluate the variation of calcium and PTH levels when adopting optical technologies compared to standard naked-eye surgery.
In total, 13 papers with 1484 procedures were included. Pooled proportion for short- and medium-term hypocalcemia rates were 8% (95% CI, 5%:11%) and 1% (95% CI, 0%:4%) for optical techniques, while for naked-eye surgery were 15% (95% CI, 9%:23%) and 5% (95% CI, 2%:9%), respectively.
Optical technologies reduced short and medium term hypocalcemia compared to conventional surgery.
NA Laryngoscope, 131:1683-1692, 2021.
目的/假设：评估光学技术对全甲状腺切除术后预防低钙血症和甲状旁腺功能减退症的影响。
系统评价和荟萃分析。
在 Pubmed、EMBASE、SCOPUS 和 Cochrane 数据库中进行文献检索。荟萃分析的合格文章的主要纳入标准为接受全甲状腺切除术的良性或恶性甲状腺病变患者、使用光学技术支持 PGs 保留、有钙和/或 PTH 水平数据。主要结局是评估与标准肉眼手术相比采用光学技术时钙和 PTH 水平的变化。
共纳入 13 篇论文，涉及 1484 例手术。光学技术的短期和中期低钙血症发生率分别为 8%（95%可信区间，5%：11%）和 1%（95%可信区间，0%：4%），而肉眼手术的发生率分别为 15%（95%可信区间，9%：23%）和 5%（95%可信区间，2%：9%）。
与传统手术相比，光学技术可降低短期和中期低钙血症的发生风险。
无。Laryngoscope, 131:1683-1692, 2021.
