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口腔物种中的微生物相互作用和免疫反应。

Microbial interactions and immunity response in oral species.

机构信息

Department of Microbiology & Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, 842 15 Bratislava, Slovakia.

Department of Chemical Engineering, LEPABE - Laboratory for Process Engineering, Environment, Biotechnology & Energy, Faculty of Engineering, University of Porto, Portugal.

出版信息

Future Microbiol. 2020 Nov;15:1653-1677. doi: 10.2217/fmb-2020-0113. Epub 2020 Nov 30.

Abstract

Oral candidiasis are among the most common noncommunicable diseases, related with serious local and systemic illnesses. Although these infections can occur in all kinds of patients, they are more recurrent in immunosuppressed ones such as patients with HIV, hepatitis, cancer or under long antimicrobial treatments. continues to be the most frequently identified spp. in these disorders, but other non- are rising. Understanding the immune responses involved in oral spp. infections is a key feature to a successful treatment and to the design of novel therapies. In this review, we performed a literature search in PubMed and WoS, in order to examine and analyze common oral spp.-bacteria/ interactions and the host immunity response in oral candidiasis.

摘要

口腔念珠菌病是最常见的非传染性疾病之一,与严重的局部和全身疾病有关。虽然这些感染可能发生在各种患者中,但在免疫抑制患者中更为常见,如 HIV、肝炎、癌症或长期接受抗生素治疗的患者。白色念珠菌仍然是这些疾病中最常被识别的 种,但其他非白色念珠菌也在上升。了解口腔念珠菌感染中涉及的免疫反应是成功治疗和设计新型疗法的关键特征。在这篇综述中,我们在 PubMed 和 WoS 上进行了文献检索,以检查和分析口腔念珠菌病中常见的口腔 种-细菌/相互作用和宿主免疫反应。

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