Meakins-Christie Laboratories, Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill University Health Centre and McGill International TB Centre, McGill University, Montreal, QC, Canada.
Bandim Health Project, Bissau, Guinea-Bissau.
Nat Immunol. 2021 Jan;22(1):2-6. doi: 10.1038/s41590-020-00845-6.
The similarities and differences between trained immunity and other immune processes are the subject of intense interrogation. Therefore, a consensus on the definition of trained immunity in both in vitro and in vivo settings, as well as in experimental models and human subjects, is necessary for advancing this field of research. Here we aim to establish a common framework that describes the experimental standards for defining trained immunity.
训练免疫与其他免疫过程之间的相似性和差异性是目前激烈讨论的主题。因此,为了推动这一研究领域的发展,有必要在体外和体内环境、实验模型和人体研究中对训练免疫的定义达成共识。在这里,我们旨在建立一个通用框架,用以描述定义训练免疫的实验标准。