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同期手术治疗单侧角膜缘干细胞缺乏和化学性烧伤后睑球粘连。

Simultaneous surgical management of unilateral limbal stem cell deficiency and symblepharon post chemical burn.

机构信息

The Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India.

The Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India

出版信息

BMJ Case Rep. 2020 Dec 9;13(12):e237234. doi: 10.1136/bcr-2020-237234.

Abstract

A 6-year-old female child presented with severe acute ocular chemical burn in the right eye 2 days after injury with cement. She underwent removal of all foreign bodies from the ocular surface and amniotic membrane transplantation. Three months later, she developed unilateral total limbal stem cell deficiency (LSCD) with symblepharon in two quadrants. Three months after the acute injury, the patient underwent autologous simple limbal epithelial transplant in the right eye with one-clock hour of limbus harvested from the left eye. At the same sitting, she underwent symblepharon release in two quadrants of the right eye with conjunctival autograft harvested from the left eye followed by conjunctival graft suturing to the areas of bare sclera in the right eye. One year after surgery, the patient's visual acuity improved from counting fingers close to face preoperatively to 20/50 (uncorrected) with no recurrence of LSCD or symblepharon.

摘要

一名 6 岁女性患儿,右眼被水泥烧伤后 2 天,出现严重急性眼部化学灼伤。她接受了眼表异物清除和羊膜移植。3 个月后,她发展为单侧全角结膜干细胞缺乏症(LSCD)伴 2 象限性睑球粘连。急性损伤后 3 个月,患者右眼行自体单时钟眼角膜缘上皮移植术,从左眼采集 1 时钟眼角膜缘。同时,她在右眼 2 象限行睑球粘连松解术,从左眼采集结膜自体移植物,随后将结膜移植物缝合至右眼暴露巩膜区。术后 1 年,患者视力从术前近脸指数提高至 20/50(未矫正),无 LSCD 或睑球粘连复发。

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