Naghdi Tina, Faham Shadab, Mahmoudi Tohid, Pourreza Nahid, Ghavami Raouf, Golmohammadi Hamed
Nanosensor Bioplatforms Laboratory, Chemistry and Chemical Engineering Research Center of Iran, Tehran 14335-186, Iran.
Chemometrics Laboratory, Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj 66177-15175, Iran.
ACS Sens. 2020 Dec 24;5(12):3770-3805. doi: 10.1021/acssensors.0c02101. Epub 2020 Dec 10.
Because of numerous inherent and unique characteristics of phytochemicals as bioactive compounds derived from plants, they have been widely used as one of the most interesting nature-based compounds in a myriad of fields. Moreover, a wide variety of phytochemicals offer a plethora of fascinating optical and electrochemical features that pave the way toward their development as optical and electrochemical (bio)sensors for clinical/health diagnostics, environmental monitoring, food quality control, and bioimaging. In the current review, we highlight how phytochemicals have been tailored and used for a wide variety of optical and electrochemical (bio)sensing and bioimaging applications, after classifying and introducing them according to their chemical structures. Finally, the current challenges and future directions/perspective on the optical and electrochemical (bio)sensing applications of phytochemicals are discussed with the goal of further expanding their potential applications in (bio)sensing technology. Regarding the advantageous features of phytochemicals as highly promising and potential biomaterials, we envisage that many of the existing chemical-based (bio)sensors will be replaced by phytochemical-based ones in the near future.
由于植物化学物质作为源自植物的生物活性化合物具有众多内在和独特的特性,它们已被广泛用作众多领域中最有趣的基于天然的化合物之一。此外,各种各样的植物化学物质具有大量引人入胜的光学和电化学特性,为其发展成为用于临床/健康诊断、环境监测、食品质量控制和生物成像的光学和电化学(生物)传感器铺平了道路。在当前的综述中,我们在根据植物化学物质的化学结构对其进行分类和介绍之后,重点强调了它们是如何被定制并用于各种光学和电化学(生物)传感及生物成像应用的。最后,讨论了植物化学物质在光学和电化学(生物)传感应用方面当前面临的挑战以及未来的方向/前景,目标是进一步扩大它们在(生物)传感技术中的潜在应用。鉴于植物化学物质作为极有前景和潜力的生物材料的优势特性,我们设想在不久的将来,许多现有的基于化学的(生物)传感器将被基于植物化学物质的传感器所取代。