增强型术后康复在伴血友病 A 的全膝关节置换患者中的应用：一项初步研究。
Application of enhanced recovery after surgery in total knee arthroplasty in patients with haemophilia A: A pilot study.
机构信息
Bone & Joint Surgery Department Shandong Provincial Qianfoshan Hospital Shandong University Jinan China.
Department of Orthopedics Affiliated Hospital of Shandong University of Traditional Chinese Medicine Jinan China.
出版信息
Nurs Open. 2020 Aug 28;8(1):80-86. doi: 10.1002/nop2.605. eCollection 2021 Jan.
AIM
To identify the effect of enhanced recovery after surgery (ERAS) and rapid rehabilitation concepts on the outcomes of patients with haemophilia A undergoing total knee arthroplasty.
DESIGN
Randomized controlled trial.
METHODS
The primary endpoint was postoperative hospital stay. The secondary endpoints were pain scores, joint function scores, haemoglobin levels at 3 and 7 days after surgery and satisfaction with hospitalization.
RESULTS
Thirty-two patients were enrolled. Compared with the routine nursing group, the ERAS group showed shorter postoperative hospital stay (14.2 0.8 vs. 16.6 ± 1.3 days, < .001), smaller amounts of blood transfusion (924 317 vs. 1,263 449 ml, = .020) and coagulation factors (37,325 5,996 vs. 48,475 8,019 U, < .001), lower pain scores at 3 (3.3 0.7 vs. 4.3 0.7, = .002) and 7 (2.3 SD 0.7 vs. 2.8 ± 0.5, = .015) days, lower hospital for special surgery knee scores at 3 (59.9 7.8 vs. 53.6 SD 5.9, = .016) and 7 (77.9 6.9 vs. 71.1 ± 7.1, = .009) days and higher satisfaction with hospitalization (94.3 1.4 vs. 92.7 1.6, = .004).
目的
确定术后快速康复（ERAS）和快速康复理念对接受全膝关节置换术的血友病 A 患者结局的影响。
设计
随机对照试验。
方法
主要终点是术后住院时间。次要终点是疼痛评分、关节功能评分、术后第 3 天和第 7 天的血红蛋白水平以及对住院的满意度。
结果
共纳入 32 例患者。与常规护理组相比，ERAS 组术后住院时间更短（14.2 0.8 比 16.6 1.3 天，<0.001），输血更少（924 317 比 1,263 449 ml，=0.020）和凝血因子更少（37,325 5,996 比 48,475 8,019 U，<0.001），术后第 3 天（3.3 0.7 比 4.3 0.7，=0.002）和第 7 天（2.3 SD 0.7 比 2.8 0.5，=0.015）疼痛评分更低，术后第 3 天（59.9 7.8 比 53.6 SD 5.9，=0.016）和第 7 天（77.9 6.9 比 71.1 7.1，=0.009）的美国特种外科医院膝关节评分更低，对住院的满意度更高（94.3 1.4 比 92.7 1.6，=0.004）。
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