Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Department of Pain Management, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Sci Rep. 2020 Dec 16;10(1):22036. doi: 10.1038/s41598-020-79209-x.
A retrospective study investigated the results of the lamina with spinous process (LSP) as a bone graft in one-level thoracic or lumbar spinal tuberculosis with the one-stage posterior approach of debridement, fusion and internal instrumentation. Data from 35 patients from January 2013 to December 2015 were analysed. Surgery time, blood loss, hospitalization time, drainage volume, and follow-up (FU) duration were recorded. The visual analogue scale (VAS), Oswestry Disability Index (ODI), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), American Spinal Injury Association (ASIA) grade, segmental angle, and bone fusion were compared between preoperative and final FU. All of the patients were followed up for a mean 43.90 ± 10.39 months. The mean age, surgery time, blood loss, hospitalization time, hospital cost and drainage volume were 33.65 ± 11.06 years, 182.40 ± 23.82 min, 280.80 ± 76.82 mL, 14.05 ± 3.58 days, 74,382.00 ± 11,938.00 yuan, and 340.00 ± 167.20 mL, respectively. VAS and ODI were significantly improved at the final FU. The ESR and CRP recovered to normal. The mean angle of 24.35 ± 5.74°preoperatively showed a significant difference between 1 week, postoperatively and final FU. Although there were the loss of angle at final FU comparing with the 1 week postoperatively, it still maintain the good alignment and the segmental stability. All patients achieved bony fusion with a mean time of 12.90 ± 3.91 months. In conclusion, the LSP as a structural bone graft is reliable, safe and effective for segmental stability reconstruction, which could be one choice for surgical management of thoracic or lumbar spinal TB.
一项回顾性研究调查了经后路一期清创、融合和内固定治疗单节段胸腰椎结核时,棘突椎板(LSP)作为骨移植物的结果。对 2013 年 1 月至 2015 年 12 月的 35 例患者的数据进行了分析。记录手术时间、失血量、住院时间、引流量和随访(FU)时间。比较术前和最终 FU 时的视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)、红细胞沉降率(ESR)、C 反应蛋白(CRP)、美国脊髓损伤协会(ASIA)分级、节段角度和骨融合。所有患者平均随访 43.90±10.39 个月。平均年龄、手术时间、失血量、住院时间、住院费用和引流量分别为 33.65±11.06 岁、182.40±23.82 分钟、280.80±76.82ml、14.05±3.58 天、74382.00±11938.00 元、340.00±167.20ml。最终 FU 时 VAS 和 ODI 明显改善。ESR 和 CRP 恢复正常。术前平均角度 24.35±5.74°与术后 1 周和最终 FU 时相比有显著差异。尽管最终 FU 时的角度与术后 1 周相比有丢失,但仍保持良好的对线和节段稳定性。所有患者均在 12.90±3.91 个月时获得骨性融合。总之,LSP 作为结构性植骨物用于重建节段稳定性是可靠、安全且有效的,可为胸腰椎结核的手术治疗提供一种选择。