Mistry Anuja Mahesh, Patel Rutul, Mistry Mahesh, Menon Varna
Internal Medicine, Smt Nathiba Hargovandas Lakhmichand Municipal Medical College, Ahmedabad, IND.
Internal Medicine, Smt. Nathiba Hargovandas Lakhmichand Municipal Medical College, Ahmedabad, IND.
Cureus. 2020 Nov 12;12(11):e11456. doi: 10.7759/cureus.11456.
Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the presence of numerous granulomas associated with loss of elastic fibers that appear to be ingested by multi-nucleated giant cells. Here, we present a case of a 56-year-old woman with multiple, anatomically variable erythematous lesions- annular and papular, mainly in the upper body. The clinical presentation and histopathologic findings support our diagnosis.
环状弹性组织溶解性巨细胞肉芽肿(AEGCG)是一种罕见的、通常自限性的慢性炎症性疾病,主要发生于手部背部、手臂伸侧、面部、颈部前方和上胸部等暴露于阳光的部位。其特征性组织学表现包括存在大量肉芽肿,伴有弹性纤维缺失,这些弹性纤维似乎被多核巨细胞吞噬。在此,我们报告一例56岁女性病例,其身上有多个形态各异的红斑性皮损——环状和丘疹状,主要分布在上半身。临床表现和组织病理学发现支持我们的诊断。