低频电刺激对大鼠跟腱愈合影响的张力测定评估
Tensiometric evaluation of the effect of lowfrequency electric stimulation on healing Achilles tendons in rats.
作者信息
Casagrande Sharbo Martins, Biondo-Simões Maria de Lourdes Pessole, Berti Lucas Freitas, Robes Rogério Ribeiro, Biondo-Simões Rachel, Nakadomari Thaísa Sami, Henning Junior Lucélio
机构信息
Fellow Master Degree, Postgraduate Program in Clinical Surgery, Universidade Federal do Paraná, Curitiba-PR, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; manuscript writing; critical revision; final approval.
Full Professor, Department of Surgery, and Permanent Professor, Postgraduate Program in Clinical Surgery, Universidade Federal do Paraná, Curitiba-PR, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; critical revision; final approval.
出版信息
Acta Cir Bras. 2020 Dec 18;35(11):e351103. doi: 10.1590/ACB351103. eCollection 2020.
PURPOSE
To evaluate the effects of low-frequency electric stimulation on biomechanics following surgical treatment of the Achilles tendon in rats.
METHODS
Forty-two rats were divided into two groups. One was given electric stimulation and the other was not. All were submitted to Achilles tenotomy and tenorrhaphy performed with a modified Kessler stitch. The experiment group underwent electric stimulation with 2 Hz, a nonpolarized current of 1 mA intensity for 14 days. The animals were euthanized at 2, 4 and 6 weeks for the biomechanical study.
RESULTS
The work performed, that is, the tendon's capacity to absorb energy until rupture, was greater in the electrically stimulated group in the 2nd (p = 0.032) and in the 6th week (p = 0.010). The maximum tension, which is the capacity to support a load, was higher in the treated group in the 2nd (p = 0.030) and the 6th week (p = 024). These results indicate greater resistance of the electrically stimulated tendons. An analysis of the elastic module showed no differences.
CONCLUSION
Low-frequency electric stimulation increased the resistance of the tendons at 2 and 6 weeks of evolution in rats.
目的
评估低频电刺激对大鼠跟腱手术治疗后生物力学的影响。
方法
42只大鼠分为两组。一组给予电刺激，另一组不给予。所有大鼠均接受跟腱切断术并用改良凯斯勒缝合法进行肌腱缝合。实验组接受频率为2Hz、强度为1mA的非极化电流电刺激，持续14天。在第2、4和6周对动物实施安乐死以进行生物力学研究。
结果
在第2周（p = 0.032）和第6周（p = 0.010），电刺激组所做的功，即肌腱直至断裂吸收能量的能力，更大。最大张力，即承受负荷的能力，在第2周（p = 0.030）和第6周（p = 0.024）时，治疗组更高。这些结果表明电刺激肌腱的抵抗力更强。弹性模量分析显示无差异。
结论
低频电刺激在大鼠术后2周和6周时增加了肌腱的抵抗力。
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