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新冠病毒病:对巴西里约热内卢一家联邦医院收治的疑似病例及其与医院死亡相关因素的横断面研究

COVID-19: a cross-sectional study of suspected cases admitted to a federal hospital in Rio de Janeiro, Brazil, and factors associated with hospital death.

作者信息

Escosteguy Claudia Caminha, Eleuterio Tatiana de Araujo, Pereira Alessandra Gonçalves Lisbôa, Marques Marcio Renan Vinícius Espínola, Brandão Amanda Dantas, Batista Juliana Paranhos Moreno

机构信息

Hospital Federal dos Servidores do Estado, Serviço de Epidemiologia, Rio de Janeiro, RJ, Brasil.

Universidade Federal do Rio de Janeiro, Instituto de Estudos em Saúde Coletiva, Rio de Janeiro, RJ, Brasil.

出版信息

Epidemiol Serv Saude. 2020 Dec 18;30(1):e2020750. doi: 10.1590/S1679-49742021000100023. eCollection 2020.

Abstract

OBJECTIVE

To describe the clinical and epidemiological profile of suspected COVID-19 cases admitted to a federal hospital in Rio de Janeiro, RJ, Brazil, and to identify factors associated with death.

METHODS

This was a cross-sectional study using local epidemiological surveillance data as at epidemiological week 27 of 2020 and logistic regression.

RESULTS

376 hospitalized suspected COVID-19 cases were included; 52.9% were female, 57.4% were 50 years old or over and 80.1% had comorbidities. 195 (51.9%) COVID-19 cases were confirmed and their lethality was higher (37.9%) than among discarded cases (24.2%). In the adjusted analysis, death among confirmed cases was associated with being in the 50-69 age group (OR=11.65 - 95%CI 1.69;80.33), being aged 70 or over (OR=8.43 - 95%CI 1.22;58.14), presence of neoplasms (OR=4.34 - 95%CI 1.28;14.76) and use of invasive ventilatory support (OR=70.20 - 95%CI 19.09;258.19).

CONCLUSION

High prevalence of comorbidities and lethality was found; the main factors associated with death were being older, neoplasms and invasive ventilatory support.

摘要

目的

描述巴西里约热内卢一家联邦医院收治的疑似新型冠状病毒肺炎(COVID-19)病例的临床和流行病学特征,并确定与死亡相关的因素。

方法

这是一项横断面研究,使用了2020年第27周的当地流行病学监测数据和逻辑回归分析。

结果

纳入376例住院疑似COVID-19病例;52.9%为女性,57.4%年龄在50岁及以上,80.1%有合并症。195例(51.9%)COVID-19病例得到确诊,其致死率(37.9%)高于排除病例(24.2%)。在调整分析中,确诊病例中的死亡与年龄在50-69岁组(比值比[OR]=11.65 - 95%置信区间[CI] 1.69;80.33)、70岁及以上(OR=8.43 - 95%CI 1.22;58.14)、存在肿瘤(OR=4.34 - 95%CI 1.28;14.76)以及使用有创通气支持(OR=70.20 - 95%CI 19.09;258.19)有关。

结论

发现合并症和致死率的患病率较高;与死亡相关的主要因素是年龄较大、肿瘤和有创通气支持。

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