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拇指重复畸形的矫正:手术技术的系统评价

Correction of Thumb Duplication: A Systematic Review of Surgical Techniques.

作者信息

Miller Robert, Kaempfen Alexandre, Moledina Jamil, Sivakumar Bran, Smith Gill, Nikkhah Dariush

机构信息

Department of Plastic Surgery, Royal Free Hospital, London, United Kingdom.

Department of Plastic Surgery, University Hospital Basel, Basel, Switzerland.

出版信息

J Hand Microsurg. 2020 Aug;12(2):74-84. doi: 10.1055/s-0039-1700445. Epub 2019 Nov 22.

Abstract

Surgical intervention for thumb duplication can be divided into three categories: simple excision of the accessory thumb, excision of the accessory thumb with reconstruction from available "spare parts," and combining the two thumbs into one, as described by Bilhaut. This prospectively PROSPERO registered systematic review evaluates the overall, aesthetic and functional outcomes for the latter two options (reconstruction from spare parts vs. combining two thumbs into one), aiming to facilitate evidence-based decision making when addressing thumb duplication and direct future research. The review was performed in accordance with the Cochrane Handbook of Systematic Reviews and PRISMA statement. Embase, PubMed, Medline, and Cochrane databases were systematically searched. Studies offering comparisons of techniques were included. Risk of bias was assessed using the Risk of Bias In Non-randomized Studies-of Intervention tool. The quality of the evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation. Ten retrospective observational studies were included. Data did not consistently allow analysis by procedure type. Four studies reported similar overall outcomes between techniques, while two specifically reported poor overall outcomes for the Bilhaut procedure. Two studies reported comparatively worse aesthetic outcomes for the Bilhaut procedure with four studies reporting comparatively improved functional outcomes for this procedure. Overall, interpretation of outcomes was challenging with no patient-reported outcome measures used. The quality of the evidence was universally "very low" due to all studies being at risk of methodological bias. Based on the available evidence, surgical techniques for thumb duplication correction appear comparable regarding overall outcome. There is limited evidence suggesting reconstruction with spare parts offers superior aesthetic outcomes at the expense of stability. The level of evidence is III.

摘要

拇指重复畸形的手术干预可分为三类

单纯切除副拇指、切除副拇指并利用可用的“备用组织”进行重建,以及如比尔奥(Bilhaut)所描述的将两个拇指合并为一个。这项前瞻性在PROSPERO注册的系统评价评估了后两种选择(利用备用组织重建与将两个拇指合并为一个)的总体、美学和功能结果,旨在为处理拇指重复畸形时基于证据的决策提供便利,并指导未来的研究。该评价按照《Cochrane系统评价手册》和PRISMA声明进行。对Embase、PubMed、Medline和Cochrane数据库进行了系统检索。纳入了对技术进行比较的研究。使用非随机干预研究中的偏倚风险工具评估偏倚风险。使用推荐分级、评估、制定和评价方法评估证据质量。纳入了十项回顾性观察性研究。数据并不始终允许按手术类型进行分析。四项研究报告了不同技术之间总体结果相似,而两项研究特别报告了比尔奥手术的总体结果较差。两项研究报告了比尔奥手术的美学结果相对较差,四项研究报告了该手术的功能结果相对改善。总体而言,由于未使用患者报告的结局指标,结果的解读具有挑战性。由于所有研究都存在方法学偏倚风险,证据质量普遍“非常低”。基于现有证据,拇指重复畸形矫正的手术技术在总体结果方面似乎相当。有有限的证据表明,利用备用组织进行重建以牺牲稳定性为代价可提供更好的美学结果。证据级别为III级。

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