Department of Radiology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Department of Radiology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
J Clin Neurosci. 2021 Jan;83:1-7. doi: 10.1016/j.jocn.2020.11.047. Epub 2020 Dec 16.
Paraclinoid aneurysms are mainly intradural, and are associated with a potential risk of subarachnoid hemorrhage (SAH). The application of stent-assisted coiling has been widely used in endovascular treatment of intracranial aneurysms. Here we aimed to compare clinical outcomes between low-profile visualized intraluminal support stents (LVIS) and Neuroform (NU) stents. Between January 2013 and December 2017, a total of 101 patients with 118 unruptured paraclinoid aneurysms were embolized by LVIS or NU stents. Procedure-related complications, angiography, and follow-up results were retrospectively analyzed. A total of 45 patients with 54 aneurysms received LVIS stents, and 56 patients with 64 aneurysms received NU stents. Procedure-related complication rate was 6.7% in the LVIS group and 5.4% in the NU group, with no statistical differences between groups (P = 0.511). Compared with the NU group, greater initial complete or near-complete aneurysm obliteration was achieved in the LVIS group (79.6% vs 59.4%, P = 0.0192). DSA angiography follow-up imaging of the 118 aneurysms showed that the LVIS group increased in Raymond-Roy Grade Scale I (RRGS I), however there is no statistical difference (P = 0.32). Compared with NU stents, LVIS stents may achieve greater complete or near-complete occlusion rate immediately post-operation. However, there was no difference in procedural-related complications and follow-up outcomes between LVIS and NU stent groups.
瘤周动脉瘤主要为硬脑膜内,且与蛛网膜下腔出血(SAH)的潜在风险相关。支架辅助弹簧圈栓塞术已广泛应用于颅内动脉瘤的血管内治疗。本研究旨在比较低剖面可视化腔内支撑支架(LVIS)和 Neuroform(NU)支架的临床治疗效果。2013 年 1 月至 2017 年 12 月,共有 101 例 118 个未破裂的瘤周动脉瘤患者接受 LVIS 或 NU 支架栓塞治疗。回顾性分析患者的操作相关并发症、血管造影和随访结果。45 例 54 个动脉瘤患者接受 LVIS 支架治疗,56 例 64 个动脉瘤患者接受 NU 支架治疗。LVIS 组操作相关并发症发生率为 6.7%,NU 组为 5.4%,两组间差异无统计学意义(P=0.511)。与 NU 组相比,LVIS 组患者初始完全或接近完全的动脉瘤闭塞率更高(79.6% vs 59.4%,P=0.0192)。对 118 个动脉瘤的 DSA 血管造影随访影像学检查显示,LVIS 组患者 Raymond-Roy 分级量表(RRGS)Ⅰ级比例增加,但差异无统计学意义(P=0.32)。与 NU 支架相比,LVIS 支架术后即刻可获得更高的完全或接近完全闭塞率。然而,LVIS 和 NU 支架组在操作相关并发症和随访结果方面无差异。