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COVID-19 大流行期间血液系统恶性肿瘤的管理。

The management of hematologic malignancies during the COVID-19 pandemic.

机构信息

Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

Department of Clinical Transplantology, Medical University of Lublin, Poland.

出版信息

Expert Opin Pharmacother. 2021 Apr;22(5):565-582. doi: 10.1080/14656566.2020.1849143. Epub 2020 Dec 21.

Abstract

: Patients with hematological malignancies have experienced a more severe clinical course of COVID-19 and higher mortality than those with solid tumors and those without cancer. The ongoing pandemic poses many challenges in assuring the correct and timely diagnosis of hemato-oncology patients as well as the optimal treatment.: The present paper reviews current data on the incidence and clinical course of COVID-19 in patients with hematological malignancies. A literature review of the MEDLINE database for articles was conducted via PubMed. Publications from December 2019 through September 2020 were scrutinized. The search terms used were OR in conjunction with OR OR OR OR . Recommendations and expert opinions either published or presented on ASH, ASCO, ESMO, NCCN websites were also reviewed.: The COVID-19 pandemic has brought a pressing need to improve the management of patients with hematological malignancies, including establishing prompt diagnoses and providing effective treatment while also minimalizing the risk of SARS-Cov2 infection. The recommendations developed by many organizations based on expert opinions are helpful in making proper decisions. All cancer patients should be advised to get vaccinated against influenza and pneumococcus.

摘要

患有血液系统恶性肿瘤的患者在 COVID-19 感染中的临床过程比患有实体瘤的患者以及无癌症患者更为严重,死亡率更高。持续的大流行在确保血液肿瘤患者的正确和及时诊断以及最佳治疗方面带来了许多挑战。

本文综述了血液系统恶性肿瘤患者 COVID-19 的发病率和临床过程的现有数据。通过 PubMed 在 MEDLINE 数据库中对文章进行了文献复习。仔细研究了 2019 年 12 月至 2020 年 9 月的出版物。使用的搜索词是 COVID-19 或 SARS-CoV-2 或 2019 年冠状病毒病 或 急性呼吸窘迫综合征 或 冠状病毒病 2019 或 严重急性呼吸综合征冠状病毒 2。还审查了 ASH、ASCO、ESMO、NCCN 网站上发表或提出的建议和专家意见。

COVID-19 大流行迫切需要改进血液系统恶性肿瘤患者的管理,包括及时诊断和提供有效治疗,同时尽量减少 SARS-CoV-2 感染的风险。许多组织根据专家意见制定的建议有助于做出正确的决策。应建议所有癌症患者接种流感和肺炎球菌疫苗。

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