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伴有肺转移的骶骨和胸椎脊索瘤:病例报告及文献复习

Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature.

作者信息

Bai Rui, Zhao Zhen-Qun, Wang Yu-Xin, Zhao Wei, Wu Li-Shuan, Cui Shu-Xia, Guo Shi-Bing, Liang Chen-Liang

机构信息

Department of Orthopedic Surgery, Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010030, P.R. China.

出版信息

Mol Clin Oncol. 2021 Jan;14(1):17. doi: 10.3892/mco.2020.2179. Epub 2020 Nov 26.

Abstract

Chordoma is a sporadic type of cancer that affects the spine and is particularly challenging to treat due to the paucity of reported cases and scientific literature. In particular, primary chordomas affecting both the sacral and thoracic vertebrae are extremely rare. We herein report a rare case of chordoma in the sacral and thoracic vertebrae with pulmonary metastasis, along with a literature review. The objective of the present study was to explore treatment options and long-term outcomes in patients with metastatic chordoma. Posterior decompression was performed for the thoracic tumor, followed by extended resection of the sacral tumor. The symptoms of the patient were relieved after surgery, and the postoperative Nurick score decreased from grade 3 to grade 2, while the postoperative McCormick score was I. Therefore, complete chordoma excision and internal spinal fixation may effectively reduce tumor recurrence and metastasis.

摘要

脊索瘤是一种散发性癌症,会影响脊柱,由于报告的病例和科学文献较少,其治疗极具挑战性。特别是,同时累及骶椎和胸椎的原发性脊索瘤极为罕见。我们在此报告一例罕见的骶椎和胸椎脊索瘤伴肺转移病例,并进行文献复习。本研究的目的是探讨转移性脊索瘤患者的治疗选择和长期预后。对胸椎肿瘤进行了后路减压,随后对骶椎肿瘤进行了扩大切除。患者术后症状缓解,术后Nurick评分从3级降至2级,术后McCormick评分为I级。因此,完整切除脊索瘤并进行脊柱内固定可有效减少肿瘤复发和转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4179/7725214/3408efa6b37e/mco-14-01-02179-g00.jpg

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