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一名糖尿病患者并发脑鼻眶毛霉菌病和曲霉菌病:病例报告

Cerebro-rhino-orbital mucormycosis and aspergillosis coinfection in a patient with diabetes mellitus: A case report.

作者信息

Zayet Souheil, Zaghdoudi Aida, Ammari Lamia, Kilani Badreddine, Tiouiri Benaissa Hanene

机构信息

Department of Infectious Diseases, La Rabta Hospital, Tunisia.

出版信息

IDCases. 2020 Dec 9;23:e01022. doi: 10.1016/j.idcr.2020.e01022. eCollection 2021.

Abstract

Opportunistic fungal infections are life-threatening conditions with a high rate of morality, mostly occurring in immunocompromised hosts. We reported the case of mixed mold infection in a 69 year-old patient with latent diabetes mellitus. She was initially admitted for right orbital cellulitis. Cerebro-rhino-orbital mucormycosis and aspergillosis coinfection was diagnosed from mycological testing and histology after nasal biopsy sample. The patient received amphotericin B deoxycholate then voriconazole combined to surgical debridement with a favorable outcome.

摘要

机会性真菌感染是一种危及生命的疾病,死亡率很高,主要发生在免疫功能低下的宿主中。我们报告了一例69岁潜伏性糖尿病患者发生混合霉菌感染的病例。她最初因右眼眶蜂窝织炎入院。经鼻活检样本的真菌学检测和组织学检查,诊断为脑鼻眶毛霉菌病和曲霉菌病合并感染。患者接受了去氧胆酸盐两性霉素B治疗,随后使用伏立康唑并联合手术清创,结果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b80f/7750555/cd4c1432f502/gr1.jpg

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