Kazi Mufaddal, Shrikhande Shailesh V, Chaudhari Vikram A, Kurunkar Sagar, Bhandare Manish S
Department of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Indian J Surg Oncol. 2020 Sep;11(Suppl 2):278-281. doi: 10.1007/s13193-020-01189-1. Epub 2020 Aug 29.
Gastric cancer perforations are rare events with management options ranging from lavage and perforation closure, to resection. Usual aim is to perform a damage control procedure, and very few patients are suitable for a curative resection. We report the first case of emergency gastrectomy with pancreatico-duodenectomy performed in emergency for a perforated stomach cancer with pancreatic head invasion. The patient was a 32-year-old gentleman who presented with a perforated antro-pyloric cancer with infiltration of pancreatic head. Emergency radical gastrectomy with en-bloc pancreatico-duodenectomy was performed with due considerations to the patient and disease factors. He had an uneventful postoperative recovery and remains disease free at 18 months of follow-up after having received adjuvant chemotherapy. Curative resections should be selectively offered in advanced (T4b) gastric cancers in patients without multiple adverse factors. In an emergency situation with perforation peritonitis, if the magnitude of resection is deemed unlikely to add to significant morbidity of the surgery, taking multiple factors into consideration, an R0 resection can offer a large survival benefit in such settings.
胃癌穿孔是罕见事件,其治疗选择范围从洗胃和穿孔闭合到切除术。通常的目标是实施损伤控制手术,很少有患者适合进行根治性切除。我们报告了首例因胃穿孔癌侵犯胰头而在急诊情况下进行急诊胃切除术加胰十二指肠切除术的病例。患者是一名32岁男性,因胃窦幽门部穿孔癌伴胰头浸润就诊。在充分考虑患者和疾病因素后,进行了急诊根治性胃切除术并整块切除胰十二指肠。他术后恢复顺利,在接受辅助化疗后的18个月随访中无疾病复发。对于没有多种不利因素的晚期(T4b)胃癌患者,应选择性地进行根治性切除。在伴有穿孔性腹膜炎的紧急情况下,如果切除范围被认为不太可能增加手术的显著发病率,综合多方面因素考虑,R0切除在此种情况下可带来较大的生存获益。