van Heerden Marli, Mabuza Dineo
Department of Chemical Pathology, University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South Africa.
EJIFCC. 2020 Nov 20;31(4):354-361. eCollection 2020 Nov.
Galactorrhoea is the presence of breast milk secretion in non-pregnant or non-breastfeeding females. In females with galactorrhoea and amenorrhoea, hyperprolactinaemia is the most likely cause. Chest wall pathology is a known cause of hyperprolactinaemia, however there are few documented reports on galactorrhoea following burn injury to the chest wall. We report a case of an adult female patient who sustained hot water burns to her torso. Following the second skin graft failure, galactorrhoea was noted and investigated. Hyperprolactinaemia was found with normal renal and thyroid function. There were no abnormalities detected on the hormones in the hypothalamic pituitary axis and MRI. Hyperprolactinaemia was attributed to chest wall injuries causing pathological stimulation of the neural suckling reflex. The patient was treated with dopamine agonists for one month and the galactorrhoea disappeared. Treatment was discontinued on discharge and the prolactin levels remained normal upon follow-up visit to the clinic.
溢乳是指非妊娠或非哺乳期女性出现乳汁分泌的现象。在伴有溢乳和闭经的女性中,高泌乳素血症是最可能的病因。胸壁病变是高泌乳素血症的已知病因,然而,关于胸壁烧伤后发生溢乳的文献报道较少。我们报告一例成年女性患者,其躯干遭受热水烫伤。在第二次皮肤移植失败后,发现了溢乳并进行了检查。发现存在高泌乳素血症,肾功能和甲状腺功能正常。下丘脑 - 垂体轴激素及磁共振成像未检测到异常。高泌乳素血症归因于胸壁损伤导致对神经吸吮反射的病理性刺激。该患者接受多巴胺激动剂治疗一个月后溢乳消失。出院时停止治疗,门诊随访时催乳素水平仍保持正常。