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一项评估2型糖尿病患者心血管风险评分的横断面研究。

A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus.

作者信息

Sehgal Arshiya, Sibia Rps, Kaur Jasleen, Bhajni Ena, Sehgal Vijay Kumar

机构信息

Department of Pharmacology, Government Medical College, Rajindra Hospital, Patiala, Punjab, India.

Department of Medicine, Rajindra Hospital, Patiala, Punjab, India.

出版信息

Int J Appl Basic Med Res. 2020 Oct-Dec;10(4):276-279. doi: 10.4103/ijabmr.IJABMR_45_20. Epub 2020 Oct 7.

Abstract

BACKGROUND

Cardiovascular disease is the leading cause of mortality worldwide, including in low- and middle-income countries. Cardiovascular risk assessment is essential to prevent the mortality caused by diabetes.

AIM

The current study was conducted to assess the prevalence of cardiovascular risk factors in type 2 diabetes and to compare the United Kingdom Prospective Diabetes Study (UKPDS) and World Health Organization (WHO)/International Society of Hypertension (ISH) chart in assessing cardiovascular risk score.

MATERIALS AND METHODS

Cardiac risk assessments were done in fifty patients attending the medicine outpatient department in an institutional hospital after ethical clearance and taking informed consent from patients. Two assessment tools were applied on the same patient.

RESULTS

Overall, 10% of people were obese (body mass index >30). Smoking was prevalent in 20% (10/50) of patients. Hypertension was observed in 60% (30/50) of patients. Raised total cholesterol (TC) was the most common lipid abnormality affecting 94% of patients. The WHO/ISH prediction charts identified 14% and 10% of patients with cardiovascular risk category <10 and 10-20, whereas the UKPDS engine predicted 24% and 38% in the same category. In high-risk categories 30-40 and >40, the WHO/ISH score predicted a higher proportion of patients (18% and 32%) than the UKPDS engine (8% and 4%, respectively). Kappa value was calculated to calculate the degree of agreement between two tools, and it was found to be 0.781 ( < 0.01).

CONCLUSION

Raised TC and hypertension were the most prevalent risk factors. There was no significant discrepancy between two assessment tools in predicting cardiovascular risk score among type 2 diabetes mellitus patients in our study.

摘要

背景

心血管疾病是全球范围内(包括低收入和中等收入国家)的主要死亡原因。心血管风险评估对于预防糖尿病所致死亡至关重要。

目的

本研究旨在评估2型糖尿病患者心血管危险因素的患病率,并比较英国前瞻性糖尿病研究(UKPDS)和世界卫生组织(WHO)/国际高血压学会(ISH)图表在评估心血管风险评分方面的情况。

材料与方法

在获得伦理批准并取得患者知情同意后,对一家机构医院内科门诊的50名患者进行了心脏风险评估。对同一患者应用了两种评估工具。

结果

总体而言,10%的人肥胖(体重指数>30)。20%(10/50)的患者吸烟。60%(30/50)的患者患有高血压。总胆固醇(TC)升高是最常见的脂质异常,影响了94%的患者。WHO/ISH预测图表确定心血管风险类别<10和10 - 20的患者分别为14%和10%,而UKPDS引擎预测同一类别中的患者分别为24%和38%。在30 - 40和>40的高风险类别中,WHO/ISH评分预测的患者比例(分别为18%和32%)高于UKPDS引擎(分别为8%和4%)。计算kappa值以计算两种工具之间的一致程度,发现为0.781(<0.01)。

结论

TC升高和高血压是最普遍的危险因素。在我们的研究中,两种评估工具在预测2型糖尿病患者心血管风险评分方面没有显著差异。

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