[COSMOS-E简介：关于对观察性研究病因进行系统评价和Meta分析的指南]
[Introduction to COSMOS-E: Guidance on conducting systematic reviews and Meta-analyses on etiology of observational studies].
作者信息
Wang W W, Yang Z R, Zhou Q X, Shi S Y, Zhang G, Zhan S Y, Sun F
机构信息
The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Primary Care Unit, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK.
出版信息
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Dec 10;41(12):2149-2159. doi: 10.3760/cma.j.cn112338-20191024-00758.
This paper introduces the conducting systematic reviews and Meta-analyses of observational studies of etiology (COSMOS-E) and illustrates the critical issues of COSMOS-E with a published systematic review. This document provides researchers with guidance on all steps in systematic reviews of observational studies of etiology, from shaping the research question, defining exposure and outcomes, to assessing the risk of bias and statistical analysis.
本文介绍了病因观察性研究的系统评价与Meta分析（COSMOS-E），并通过一篇已发表的系统评价阐述了COSMOS-E的关键问题。本文为研究人员提供了病因观察性研究系统评价各步骤的指导，从构建研究问题、定义暴露因素和结局，到评估偏倚风险和进行统计分析。
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