Institute of Pharmaceutical Research, GLA University, Mathura-281406, Uttar Pradesh, India.
Mini Rev Med Chem. 2021;21(14):1965-1997. doi: 10.2174/1389557521999201230200503.
Herb, Zanthoxylum armatum DC., commonly called Indian prickly ash, and Nepal pepper (family Rutaceae), is widely utilized in the traditional medicinal system.
The current review provides requisite data for collecting descriptive information on the organoleptic, microscopical, ethnobotanical use, and phytochemicals and pharmacological properties of Z. armatum; therefore, it may help in forming a bridge between research gaps and the upcoming future findings for most of the researches.
The systematic literature survey was conducted using the PRISMA methodology. The collective information was gathered from books, renowned journals, and electronic databases including Science Direct, Web of Science, Scopus and PubMed from 1966 to 2020.
Most of the bioactive metabolites are isolated and characterized till date, such as monoterpenes in essential oil and lignan components are reported to be present in the herbs. Several in vitro and in vivo pharmacological bioassays revealed the potential of Z. armatum having as possessing antimicrobial, antifungal, antibacterial, and hepatoprotective effects and so on.
Therefore, the current review summarizes the organoleptic, microscopy, phytochemistry and biological activities of Z. armatum, providing more emphasis on in vitro as well as in-vivo studies along with clinical research, helpful in exploring the potential efficacy of the plant.
花椒,芸香科花椒属植物(俗称印度花椒或尼泊尔胡椒),在传统医学体系中被广泛应用。
本综述提供了必需的数据,可用于收集有关花椒的感官、微观、民族植物学用途以及植物化学和药理学特性的描述性信息;因此,它可能有助于弥合研究空白与未来大部分研究的发现之间的差距。
采用 PRISMA 方法进行系统文献综述。从书籍、知名期刊以及电子数据库(包括 Science Direct、Web of Science、Scopus 和 PubMed)中收集了 1966 年至 2020 年的资料。
迄今为止,已分离和鉴定出大部分生物活性代谢物,如精油中的单萜类化合物和木脂素成分被报道存在于草药中。多项体外和体内药理学生物测定揭示了花椒具有抗菌、抗真菌、抗细菌和保肝作用等潜在功效。
因此,本综述总结了花椒的感官、微观、植物化学和生物学活性,并特别强调了体外和体内研究以及临床研究,有助于探索该植物的潜在功效。