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复杂良性食管疾病的食管切除术

Esophagectomy for complex benign esophageal disease.

作者信息

Waters P F, Pearson F G, Todd T R, Patterson G A, Goldberg M, Ginsberg R J, Cooper J D, Ramirez J, Miller L

机构信息

University of Toronto, Division of Thoracic Surgery, Ontario, Canada.

出版信息

J Thorac Cardiovasc Surg. 1988 Mar;95(3):378-81.

PMID:3343848
Abstract

We evaluated the use of total thoracic esophagectomy and replacement with stomach in a group of 21 patients between 1976 and 1986 who had undergone multiple unsuccessful esophageal operations. All patients had between one and four unsuccessful operations for benign esophageal disorders. Sixteen patients had primary motor disorders: achalasia in nine and esophageal spasm in seven. Of these patients, 11 also had recurrent gastroesophageal reflux and peptic esophagitis. Complicated reflux disease characterized by severe esophagitis, stricture, and impaired peristalsis without primary motor disorder occurred in five patients. In one patient a functionally impaired long-segment colon interposition was removed and replaced with stomach. Total thoracic esophagectomy and cervical esophagogastric reconstruction was done in all patients. The transhiatal approach was chosen for resection in 16 patients and thoracotomy was used in the other five. There was one perioperative death (5%), from massive aspiration 4 days after transhiatal esophagectomy. Other complications included transient anastomotic leak (three patients), tracheoesophageal fistula (one), recurrent nerve palsy (one), and transient hoarseness (two). Follow-up is complete between 1 and 10 years and reveals the following functional results: 12 patients good to excellent, seven fair, one poor. In this patient group in which multiple prior procedures have failed to improve severe incapacitating symptoms, we believe further attempts at hiatal reconstruction are unlikely to succeed. For this circumstance, we recommend total thoracic esophagectomy with the use of stomach as the replacement organ of choice.

摘要

我们评估了1976年至1986年间对一组21例患者实施全胸段食管切除术并以胃代食管的情况,这些患者此前接受过多次食管手术但均未成功。所有患者因良性食管疾病接受过1至4次未成功的手术。16例患者存在原发性运动障碍:9例为贲门失弛缓症,7例为食管痉挛。其中,11例还伴有复发性胃食管反流和消化性食管炎。5例患者患有以严重食管炎、狭窄和蠕动功能受损为特征的复杂性反流疾病,且无原发性运动障碍。1例患者因功能受损的长段结肠间置术被切除,代之以胃。所有患者均接受了全胸段食管切除术及颈部食管胃重建术。16例患者选择经裂孔途径进行切除,另外5例采用开胸手术。围手术期死亡1例(5%),为经裂孔食管切除术后4天因大量误吸所致。其他并发症包括短暂性吻合口漏(3例)、气管食管瘘(例)、喉返神经麻痹(1例)和短暂性声音嘶哑(2例)。随访时间为1至10年,结果显示功能如下:12例患者良好至优秀,7例尚可,1例较差。在这组先前多次手术均未能改善严重致残症状的患者中,我们认为进一步尝试裂孔重建不太可能成功。对于这种情况,我们建议采用全胸段食管切除术,并选择胃作为替代器官。

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