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男性和女性阻塞性睡眠呼吸暂停患者的多导睡眠图、人口统计学和临床差异。

Polysomnographic, demographic and clinic differences between male and female obstructive sleep apnea patients.

机构信息

Clinic of Chest Diseases, Medicana International İzmir Hospital, İzmir, Turkey.

Department of Chest Diseases, Ankara University Faculty of Medicine, Ankara, Turkey.

出版信息

Tuberk Toraks. 2020 Dec;68(4):361-370. doi: 10.5578/tt.70359.

Abstract

INTRODUCTION

The differences between both genders with Obstructive Sleep Apnea Syndrome (OSAS) which is often seen in males can be explained by means of certain polysomnographical parameters and demographical and clinical features. The aim of this research study is to research the gender differences in Turkish population in terms of polysomnographical parameters and demographical and clinical features, and to compare and contrast the results of this research with the results of literature.

MATERIALS AND METHODS

This study has been carried out by including 100 females and 116 males, 216 patients in total, who were diagnosed with OSAS in the Sleep Laboratory of the Medicine Faculty, Ankara University between the years of 2011 and 2014. The demographical information like the ages and the genders of all patients and the figures of the height, weight and body-mass index (BMI) have been recorded. The Epworth Sleepiness Scale (ESS) of patients have also been recorded. Acquired by the polysomnography equipment, the polysomnographical data of all patients having the criteria of this study have been evaluated.

RESULT

The average age of female patients, which is 57.2 ± 9.1 (the lowestthe highest), has been found to be meaningfully high (p<0.05) when compared to the average age of male patients (50.9 ± 11.8). The body-mass index (BMI) averages of female patients, which are 35.4 ± 9.2, have been determined to be high (p<0.05) when compared to the body-mass index (BMI) average of male patients (32.5 ± 6.7). The total Apnea Hypopnea Index (AHI) of male patients have been found to be meaningfully higher than of the female patients (p<0.05). Mild and moderate OSAS in female patients have been observed at a higher rate than males. On the other hand, severe OSAS has been observed at a higher rate than females (p<0.05). Likewise, while the average obstructive apnea time in male patients has been for 17 ± 5.8 seconds, the same figure has been for 14.5 ± 4.4 seconds (p<0.05).

CONCLUSIONS

As a result, in this study, we have observed that females suffering from OSAS are older and obese at a more rate and they have lower Apnea Hypopnea Index (AHI) than the males with OSAS. We have also distinguished that the symptoms related to OSAS of both genders are similar despite the lower Apnea Hypopnea Index of females. Meanwhile we want to emphasize that clinicians need to take these factors into consideration while focusing on the diagnosis of OSAS in female patients.

摘要

介绍

阻塞性睡眠呼吸暂停综合征(OSAS)在男性中更为常见,其性别差异可以通过某些多导睡眠图参数以及人口统计学和临床特征来解释。本研究旨在探讨土耳其人群中多导睡眠图参数、人口统计学和临床特征的性别差异,并将研究结果与文献结果进行比较和对比。

材料和方法

本研究共纳入 2011 年至 2014 年间在安卡拉大学医学院睡眠实验室诊断为 OSAS 的 100 名女性和 116 名男性,共 216 名患者。记录了所有患者的年龄、性别以及身高、体重和体重指数(BMI)等人口统计学信息。还记录了患者的 Epworth 嗜睡量表(ESS)评分。通过多导睡眠图设备评估所有符合本研究标准的患者的多导睡眠图数据。

结果

女性患者的平均年龄为 57.2 ± 9.1(最低-最高),明显高于男性患者的平均年龄 50.9 ± 11.8(p<0.05)。女性患者的 BMI 平均值为 35.4 ± 9.2,明显高于男性患者的 BMI 平均值 32.5 ± 6.7(p<0.05)。男性患者的总呼吸暂停低通气指数(AHI)明显高于女性患者(p<0.05)。女性患者轻度和中度 OSAS 的发生率高于男性,而重度 OSAS 的发生率高于女性(p<0.05)。同样,男性患者的平均阻塞性呼吸暂停时间为 17 ± 5.8 秒,而女性患者的平均阻塞性呼吸暂停时间为 14.5 ± 4.4 秒(p<0.05)。

结论

因此,在本研究中,我们观察到患有 OSAS 的女性年龄更大,肥胖率更高,且 AHI 低于患有 OSAS 的男性。我们还发现,尽管女性的 AHI 较低,但两性的 OSAS 相关症状相似。同时,我们想强调,临床医生在关注女性 OSAS 患者的诊断时需要考虑这些因素。

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