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2型糖尿病患者空腹血糖及相关因素的纵向趋势

Longitudinal Trend of Fasting Blood Glucose and Related Factors in Patients with Type 2 Diabetes.

作者信息

Khatirnamani Zahra, Bakhshi Enayatollah, Naghipour Arash, Teymouri Robab, Hosseinzadeh Samaneh

机构信息

Department of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Health Center Complex, Prevention and Control of Diseases Unit, Gorgan, Iran.

出版信息

Int J Prev Med. 2020 Nov 26;11:177. doi: 10.4103/ijpvm.IJPVM_195_18. eCollection 2020.

Abstract

BACKGROUND

Control of diabetes plays an important role in improving complications and disabilities and quality of life. This study aimed to evaluate the 3-year changes in fasting blood glucose (FBG) values and its related factors in patients with type 2 diabetes.

METHODS

In this retrospective cohort study, 500 patients with type 2 diabetes covered by the National Diabetic Prevention and Care Plan during 2013-2016 were selected based on random cluster systematic sampling. A linear mixed model was used to study changes in FBG levels and their related factors. The data were analyzed using the R3.2.0 software.

RESULTS

The patients' mean age was 47.7 years. Among these patients, 58.6% were female, 19.8% had a history of smoking. High FBG was associated with high disease duration, high body mass index (BMI), low age, normal BMI at baseline, insulin therapy, smoking, and family history of diabetes. Trend of FBG in follow-up was decreasing.

CONCLUSIONS

Given that patients who received insulin therapy had higher mean FBG, it is recommended to examine their insulin dose and modifications should be made in terms of the patients' needs during their continuous follow-up. Weight loss during follow-up and cessation of smoking indicate a favorable prognosis of disease. More attention should be paid to younger patients in care. Patients are encouraged to start treatment and care at the same time diagnose.

摘要

背景

糖尿病的控制对于改善并发症、残疾情况及生活质量起着重要作用。本研究旨在评估2型糖尿病患者空腹血糖(FBG)值及其相关因素的3年变化情况。

方法

在这项回顾性队列研究中,采用随机整群系统抽样方法,选取了2013年至2016年期间纳入国家糖尿病预防与护理计划的500例2型糖尿病患者。使用线性混合模型研究FBG水平及其相关因素的变化。数据采用R3.2.0软件进行分析。

结果

患者的平均年龄为47.7岁。其中,女性占58.6%,有吸烟史的占19.8%。高FBG与病程长、体重指数(BMI)高、年龄小、基线时BMI正常、胰岛素治疗、吸烟及糖尿病家族史相关。随访期间FBG呈下降趋势。

结论

鉴于接受胰岛素治疗的患者平均FBG较高,建议检查其胰岛素剂量,并在持续随访期间根据患者需求进行调整。随访期间体重减轻和戒烟表明疾病预后良好。在护理中应更多关注年轻患者。鼓励患者在确诊时同时开始治疗和护理。

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