Sjögren B, Elinder C G, Lidums V, Chang G
Section of Occupational Medicine, National Swedish Institute of Occupational Health, Solna.
Int Arch Occup Environ Health. 1988;60(2):77-9. doi: 10.1007/BF00381484.
The urinary excretion of aluminum was measured in 23 welders before and after an exposure-free interval of 16 to 37 days. In addition, the concentration of aluminum in the air was measured at the work site of 16 aluminum welders on the same workday as the first urine sample was taken. The concentration of aluminum in the urine depended on both the level and duration of exposure. The postshift urinary concentration of aluminum prior to an exposure-free interval was mainly related to the current air concentration, whereas the urinary concentration of aluminum determined after the exposure-free interval was related to total exposure duration (years). Among welders exposed for less than 1 year, the half-time for urinary concentration was about 9 days whereas welders exposed for more than 10 years had half-times calculated to be 6 months or longer. The results indicate that aluminum is retained and stored in at least two functional compartments of the body and is eliminated from these compartments at different rates.
在23名焊工16至37天无接触期前后测量了铝的尿排泄量。此外，在采集第一份尿样的同一个工作日，在16名铝焊工的工作场所测量了空气中铝的浓度。尿中铝的浓度取决于接触水平和接触持续时间。无接触期前的班后尿铝浓度主要与当前空气浓度有关，而无接触期后的尿铝浓度与总接触持续时间（年）有关。在接触不到1年的焊工中，尿浓度的半衰期约为9天，而接触超过10年的焊工计算出的半衰期为6个月或更长。结果表明，铝在体内至少两个功能区留存和储存，并以不同速率从这些区域排出。
