Department of Medical Insurance, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.
Center for Health Development Studies, Peking University, Beijing, China.
Qual Life Res. 2021 Jun;30(6):1571-1582. doi: 10.1007/s11136-020-02751-8. Epub 2021 Jan 19.
Associations between subjective life expectancy (SLE) and a variety of factors are well documented, but the relationship regarding cancer is limited. The purpose of this study was to disclose this potential relationship and identify the covariates that might influence this relationship.
Data were extracted from the China Health and Retirement Longitudinal Study (CHARLS), and a sample of 448 cancer survivors and 43,795 individuals without cancer were analyzed. Multilevel mixed-effects logistic regression was performed to examine the SLE associated with cancer survivors and participants without cancer after controlling for demographic, socioeconomic, health-related, and psychosocial factors.
The findings revealed that cancer survivors had a 39% reduction in longer life expectancy compared to respondents without cancer. Disparities in SLE existed based on diverse individual characteristics. The rate of high SLE in urban citizens was 75% higher compared to that of rural residents, while the rate of high SLE in participants with disability fell by 55%. The rate of high SLE decreased by 22% and 35% in respondents with high blood pressure and diabetes, respectively. The proportion of respondents with high SLE was reduced by 70% when depression was present. Furthermore, the out-of-pocket expenditures of participants with and without cancer showed a significant difference, but discrepancies with respect to SLE among different cancer treatment options were not found.
The more challenging one's socioeconomic status is and the unhealthier one's physical and mental conditions are, the lower one's prospect of subjective life expectancy is. Further work is warranted to confirm the causal association between subjective life expectancy and certain characteristics in cancer survivors.
主观预期寿命(SLE)与各种因素之间的关联已有充分记录,但有关癌症的关联有限。本研究的目的是揭示这种潜在的关联,并确定可能影响这种关联的协变量。
数据取自中国健康与养老追踪调查(CHARLS),分析了 448 名癌症幸存者和 43795 名无癌症个体的数据。采用多层次混合效应逻辑回归,在控制人口统计学、社会经济、健康相关和心理社会因素后,检查癌症幸存者和无癌症参与者的 SLE 相关因素。
研究结果显示,与无癌症的受访者相比,癌症幸存者的预期寿命更长的可能性降低了 39%。基于不同的个体特征,SLE 存在差异。城市居民的高 SLE 率比农村居民高 75%,而残疾参与者的高 SLE 率则下降了 55%。高血压和糖尿病患者的高 SLE 率分别下降了 22%和 35%。有抑郁症状的患者的高 SLE 率下降了 70%。此外,癌症患者和非癌症患者的自付支出存在显著差异,但不同癌症治疗方案之间的 SLE 差异并不明显。
一个人的社会经济地位越困难,身体和心理健康状况越差,其主观预期寿命的前景就越低。需要进一步的工作来确认主观预期寿命与癌症幸存者某些特征之间的因果关联。