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COVID-19 时期急性呼吸窘迫综合征患者的俯卧位通气:从研究到实践的转变。

Prone positioning in patients with acute respiratory distress syndrome, translating research and implementing practice change from bench to bedside in the era of coronavirus disease 2019.

机构信息

Intensive Care Unit, Redcliffe Hospital, Australia; Intensive Care Unit, Caboolture Hospital, Australia; University of Queensland, Australia.

Intensive Care Unit, Redcliffe Hospital, Australia; University of Queensland, Australia.

出版信息

Aust Crit Care. 2021 Mar;34(2):176-181. doi: 10.1016/j.aucc.2020.08.002. Epub 2021 Jan 22.

Abstract

BACKGROUND

Acute respiratory distress syndrome (ARDS) is a relatively common condition of varied aetiology associated with high morbidity and mortality. A range of therapies have been proven to be useful for patients with ARDS, including ventilatory and nonventilatory strategies. Prone positioning is one of the nonventilatory strategies and has been proven to be safe and is associated with significant mortality benefit in patients with moderate to severe ARDS. It is now included in several international guidelines as the standard of care for these cases.

OBJECTIVES

The aim of the study was to develop, implement, and evaluate a prone positioning program in two nonmetropolitan, nontertiary intensive care units in South East Queensland.

METHODS

A Plan-Do-Study-Act quality improvement model was used to implement changes in clinical practice in relation to prone positioning of patients.

RESULTS

A description of the methods used to promote a complex change strategy is provided in this article.

CONCLUSIONS

In this article, we demonstrate the feasibility of introducing a nonventilatory intervention of prone positioning in the management of patients with moderate to severe ARDS in regional intensive care in South East Queensland. This implementation strategy could be replicated and adopted in other similar intensive care units that do not have the ability to provide tertiary services such as extracorporeal life support.

摘要

背景

急性呼吸窘迫综合征(ARDS)是一种病因多样的常见病症,发病率和死亡率均较高。多项疗法已被证实对 ARDS 患者有效,包括通气和非通气策略。俯卧位通气是一种非通气策略,已被证实安全,并可显著降低中重度 ARDS 患者的死亡率。目前,该策略已被纳入多项国际指南,作为此类患者的常规治疗方法。

目的

本研究旨在昆士兰州东南部两个非大都市、非三级重症监护病房(ICU)中制定、实施和评估俯卧位通气计划。

方法

采用计划-实施-研究-行动(Plan-Do-Study-Act)质量改进模型,对俯卧位通气患者的临床实践进行改进。

结果

本文详细介绍了在昆士兰州东南部地区的区域性重症监护病房中,实施一项复杂的俯卧位通气策略的方法。

结论

本文展示了在昆士兰州东南部地区的区域重症监护病房中,管理中重度 ARDS 患者时,引入非通气性俯卧位通气干预措施的可行性。该实施策略可在其他不具备体外生命支持等三级服务能力的类似重症监护病房中复制和采用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75e3/7825921/ddb6f0ff619c/gr1_lrg.jpg

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