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单个病灶中生殖器外硬化性苔藓和硬斑病的组织病理学共存

Histopathological Coexistence of Extragenital Lichen Sclerosus and Morphea in a Single Lesion.

作者信息

Almuqati Reema R, Hariri Jehad, Abduljabbar Mohammed

机构信息

Dermatology, Dr. Soliman Fakeeh Hospital, Jeddah, SAU.

Dermatology, King Abdulaziz University Hospital, Jeddah, SAU.

出版信息

Cureus. 2020 Dec 22;12(12):e12215. doi: 10.7759/cureus.12215.

Abstract

Lichen sclerosus (LS) and morphea are two infrequent inflammatory dermatoses of unknown etiology. LS is characterized by, polygonal, bluish-white, slightly elevated papules that coalesce into plaques, which become increasingly atrophic overtime.it mostly affects genitals, however, it can affect any site on the skin and mucosa. Morphea characterized by, erythematous to violaceous patches or plaque with a white, sclerotic center, and the outer edge of the lesions take on the characteristic violaceous ring. The overlapping clinical and histopathologic features of both LS and morphea in the same patient have led some to speculate that they may have a common pathologic link or that both conditions represent the same disease spectrum. The coexistence of LS and morphea in the same lesion is a rare finding. We present a patient, who was diagnosed with what appeared clinically to be extragenital LS, but with histopathologic features of both LS and morphea.

摘要

硬化性苔藓(LS)和硬斑病是两种病因不明的罕见炎症性皮肤病。LS的特征是多边形、蓝白色、略隆起的丘疹,融合成斑块,随着时间的推移会越来越萎缩。它主要影响生殖器,但也可累及皮肤和黏膜的任何部位。硬斑病的特征是红斑至紫红色斑块或斑片,中央为白色硬化,病变外缘有特征性的紫红色环。同一患者中LS和硬斑病重叠的临床和组织病理学特征使一些人推测它们可能有共同的病理联系,或者这两种情况代表同一疾病谱。LS和硬斑病在同一病变中共存是一种罕见的发现。我们报告一名患者,临床诊断为似乎是生殖器外LS,但具有LS和硬斑病的组织病理学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ced/7815259/e7031d07634e/cureus-0012-00000012215-i01.jpg

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