评估 CPAP 撤机程序对经鼻持续气道正压通气总天数的影响：一项回顾性图表审查。
Evaluating the impact of CPAP weaning procedures on total days on nasal CPAP: A retrospective chart review.
机构信息
Department of Pediatrics, Division of Neonatology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Department of Obstetrics, Gynecology and Newborn Care, Division of Neonatology, The Ottawa Hospital, General Campus, Ottawa, Ontario, Canada.
出版信息
J Neonatal Perinatal Med. 2021;14(4):537-546. doi: 10.3233/NPM-200625.
BACKGROUND
There is no consensus on how to wean infants from Nasal Continuous Positive Airway Pressure (NCPAP). We hypothesized that ceasing NCPAP abruptly would decrease the duration required, compared with a gradual wean.
METHODS
This retrospective chart review included preterm infants requiring NCPAP for over 48 hours. Cohort1 weaned NCPAP by cycling on and off, while cohort 2 ceased NCPAP abruptly. The primary outcome was total days on NCPAP. Secondary outcomes included rate of bronchopulmonary dysplasia, weight gain, duration of hospital stay, and compliance with the use of stability criteria.
RESULTS
81 infants met inclusion criteria in cohort one, and 89 in cohort two. Median days on NCPAP were 17.0 and 11.0 days, respectively, not significant. There was no significant difference in secondary outcomes.
CONCLUSIONS
There was no significant association between the two NCPAP weaning protocols and the outcomes studied.
背景
目前对于如何从经鼻持续气道正压通气（NCPAP）中逐渐撤机，尚无共识。我们假设与逐渐撤机相比，突然停止 NCPAP 会减少所需的时间。
方法
本回顾性图表研究纳入了需要使用 NCPAP 超过 48 小时的早产儿。队列 1 通过循环开启和关闭来逐渐撤机，而队列 2 则突然停止使用 NCPAP。主要结果是使用 NCPAP 的总天数。次要结果包括支气管肺发育不良的发生率、体重增加、住院时间和稳定性标准使用的依从性。
结果
队列 1 中有 81 名婴儿符合纳入标准，队列 2 中有 89 名婴儿符合纳入标准。NCPAP 使用的中位数天数分别为 17.0 天和 11.0 天，差异无统计学意义。次要结果也无显著差异。
结论
两种 NCPAP 撤机方案与所研究的结果之间无显著关联。
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