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自体脂肪移植治疗剖宫产术后腹壁瘢痕粘连

Autologous fat transplantation for the treatment of abdominal wall scar adhesions after cesarean section.

作者信息

Li Sheng-Hong, Wu Yin-Di, Wu Yan-Yun, Liao Xuan, Cheung Pik-Nga, Wan Ting, Xiao Li-Ling, Song Jian-Xing, Huang Hai-Ling, Liu Hong-Wei

机构信息

Department of Plastic Surgery, The First Affiliated Hospital, Jinan University, Key Laboratory of Regenerative Medicine, Ministry of Education, Institute for New Technologies of Plastic Surgery of Jinan University, Guangzhou, China.

Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou, China.

出版信息

J Plast Surg Hand Surg. 2021 Aug;55(4):210-215. doi: 10.1080/2000656X.2020.1856675. Epub 2021 Feb 3.

Abstract

Cesarean section results in scarring, which usually leads to adhesion between the subcutaneous fat and the abdominal wall muscle. The present study aimed to evaluate the therapeutic effect of autologous fat grafting on scar adhesion to the abdominal wall after cesarean section. Thirty-six patients with scar adhesion to the abdominal wall after cesarean section were recruited and treated between October 2013 and December 2015. The adhesion between the subcutaneous fat and the abdominal wall muscle was carefully separated through a small incision in the original scar to form multiple subcutaneous tunnels. Aspirated fat was injected into the scar lesion and subcutaneous tunnels, and the wound was then sutured. The clinical outcome was evaluated by comparing the pretreatment and 1-year posttreatment photographs and Patient and Observer Scar Assessment Scale (POSAS) scores. All patients had a marked improvement in the appearance, texture, and depression of the scar during 12 months of follow-up. The 1-year posttreatment POSAS scores for the color, pain, pruritus, hardness, fullness, mobility, and appearance of the scar were significantly decreased compared with the pretreatment scores. Hematoxylin-eosin staining revealed adipocyte-like cells in treated scar tissue specimens obtained 1 year after treatment. None of the patients reported severe adverse reactions. Autologous fat grafting combined with adhesion release may be a good treatment option for abdominal wall scarring after cesarean section. This method is minimally invasive and effective in achieving good functional and esthetic outcomes.

摘要

剖宫产会导致瘢痕形成,这通常会导致皮下脂肪与腹壁肌肉之间粘连。本研究旨在评估自体脂肪移植对剖宫产术后腹壁瘢痕粘连的治疗效果。2013年10月至2015年12月期间,招募并治疗了36例剖宫产术后腹壁瘢痕粘连患者。通过原瘢痕处的小切口仔细分离皮下脂肪与腹壁肌肉之间的粘连,形成多个皮下隧道。将抽吸的脂肪注射到瘢痕病变和皮下隧道中,然后缝合伤口。通过比较治疗前和治疗后1年的照片以及患者和观察者瘢痕评估量表(POSAS)评分来评估临床结果。在12个月的随访期间,所有患者的瘢痕外观、质地和凹陷均有明显改善。与治疗前评分相比,治疗后1年瘢痕的颜色、疼痛、瘙痒、硬度、饱满度、活动度和外观的POSAS评分显著降低。苏木精-伊红染色显示治疗1年后获得的瘢痕组织标本中有脂肪样细胞。所有患者均未报告严重不良反应。自体脂肪移植联合粘连松解可能是剖宫产术后腹壁瘢痕的一种良好治疗选择。该方法微创且能有效实现良好的功能和美学效果。

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