Department of Neurology, School of Medicine, Erciyes University, 38038, Kayseri, Turkey.
Department of Pulmonary Medicine, Ministry of Health Kayseri City Hospital, Kayseri, Turkey.
Neurol Sci. 2021 May;42(5):1661-1664. doi: 10.1007/s10072-021-05097-2. Epub 2021 Feb 3.
In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various neurological symptoms have been also described in patients with COVID-19. Here, we report an unusual presentation of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not interrupt teriflunomide treatment during the infection. The course of the infection was mild in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people with MS (pwMS). It can also be concluded that teriflunomide may be considered a safe disease-modifying treatment option during the pandemic.
2019 年 12 月,新型冠状病毒病 2019(COVID-19)在武汉出现,并迅速在中国蔓延。自大流行爆发以来,除了众所周知的 COVID-19 症状外,还在 COVID-19 患者中描述了各种神经系统症状。在这里,我们报告了一例在接受特立氟胺治疗的多发性硬化症(MS)患者中 COVID-19 感染的不寻常表现,该患者在感染期间未中断特立氟胺治疗。在这种情况下,感染的过程是轻微的,与其他报告的 COVID-19 接受特立氟胺治疗的患者一样。MS 患者(pwMS)的 COVID-19 表现可能不寻常。还可以得出结论,特立氟胺在大流行期间可能被视为一种安全的疾病修正治疗选择。