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新冠病毒感染个体在接受特立氟胺治疗多发性硬化症时,以一过性单眼视力障碍为首发症状。

Transient monocular visual impairment as an initial symptom of COVID-19 infection in an individual with multiple sclerosis receiving teriflunomide.

机构信息

Department of Neurology, School of Medicine, Erciyes University, 38038, Kayseri, Turkey.

Department of Pulmonary Medicine, Ministry of Health Kayseri City Hospital, Kayseri, Turkey.

出版信息

Neurol Sci. 2021 May;42(5):1661-1664. doi: 10.1007/s10072-021-05097-2. Epub 2021 Feb 3.

Abstract

In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various neurological symptoms have been also described in patients with COVID-19. Here, we report an unusual presentation of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not interrupt teriflunomide treatment during the infection. The course of the infection was mild in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people with MS (pwMS). It can also be concluded that teriflunomide may be considered a safe disease-modifying treatment option during the pandemic.

摘要

2019 年 12 月,新型冠状病毒病 2019(COVID-19)在武汉出现,并迅速在中国蔓延。自大流行爆发以来,除了众所周知的 COVID-19 症状外,还在 COVID-19 患者中描述了各种神经系统症状。在这里,我们报告了一例在接受特立氟胺治疗的多发性硬化症(MS)患者中 COVID-19 感染的不寻常表现,该患者在感染期间未中断特立氟胺治疗。在这种情况下,感染的过程是轻微的,与其他报告的 COVID-19 接受特立氟胺治疗的患者一样。MS 患者(pwMS)的 COVID-19 表现可能不寻常。还可以得出结论,特立氟胺在大流行期间可能被视为一种安全的疾病修正治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/7856853/6b1ad23a9d7f/10072_2021_5097_Fig1_HTML.jpg

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