J Drugs Dermatol. 2021 Feb 1;20(2):225-226. doi: 10.36849/JDD.5721.
Acitretin, a vitamin A derivative used for psoriasis, can prevent keratinocyte carcinoma (KC). It induced regression of keratoacanthomas (KA) in animal models, presumably by activating retinoic acid and retinoid X receptors that regulate gene expression for growth and proliferation.1,2.
阿维 A 酯,一种用于治疗银屑病的维生素 A 衍生物,可预防角质形成细胞癌 (KC)。它在动物模型中诱导角化棘皮瘤 (KA) 的消退,推测是通过激活调节生长和增殖的基因表达的视黄酸和维 A 酸受体。1,2。