金纳米颗粒：合成、物理化学性质及在癌症治疗中的应用。
Gold nanoparticles: synthesis, physiochemical properties and therapeutic applications in cancer.
机构信息
School of Clinical Medicine, Weifang Medical University, Weifang 261053, Shandong, China; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, New York, NY 11439, USA.
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, New York, NY 11439, USA.
出版信息
Drug Discov Today. 2021 May;26(5):1284-1292. doi: 10.1016/j.drudis.2021.01.030. Epub 2021 Feb 4.
Gold nanoparticles (AuNPs) have been shown to be useful as carriers of various anticancer drugs as well as diagnosis platforms. In this review, we discuss the synthesis and physiochemical properties of AuNPs. We also highlight the photothermal and photodynamic properties of AuNPs and relevant applications in therapeutic studies. Furthermore, we review the applications of AuNPs in cancer treatment as and their underlying anticancer mechanisms in multiple types of cancer.
金纳米粒子（AuNPs）已被证明可作为各种抗癌药物的载体以及诊断平台。在这篇综述中，我们讨论了 AuNPs 的合成和物理化学性质。我们还强调了 AuNPs 的光热和光动力性质及其在治疗研究中的相关应用。此外，我们还回顾了 AuNPs 在癌症治疗中的应用及其在多种类型癌症中的潜在抗癌机制。
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