Brzegowy Paweł, Polak Jakub, Wnuk Jakub, Łasocha Bartłomiej, Kwinta Borys, Urbanik Andrzej, Popiela Tadeusz J
Chair of Radiology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Students' Scientific Group, Chair of Radiology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Pol J Radiol. 2020 Dec 20;85:e650-e656. doi: 10.5114/pjr.2020.103204. eCollection 2020.
The middle cerebral artery (MCA) is the second most common location of intracerebral aneurysms. Traditionally, they are treated by microsurgical clipping, but with the development of new techniques and devices endovascular embolisation is gaining more importance. The aim of this study was to summarise six years of experience of our department in endovascular treatment of MCA aneurysms.
Forty patients with 41 MCA aneurysms treated in a single centre were included in this study. Data on patients' comorbidities, aneurysm morphology, and treatment course were collected, with special emphasis on complications.
There were no statistically significant differences in terms of aneurysm morphology between males and females and between ruptured and unruptured aneurysms. None of the diseases analysed in the current study were linked with significantly increased risk of SAH. Unruptured aneurysms were significantly more frequently treated by stent-assisted coiling (30.4% vs. 5.6%, = 0.0388) than were ruptured aneurysms, while ruptured aneurysms were treated more frequently by coiling alone (77.8% vs. 34.8%, = 0.0062). After an initial course of treatment 63.4% ( = 26) of patients had class I in Raymond-Roy occlusion classification, 22% ( = 9) had class II, and 14.6% ( = 6) had class III. Complications of the procedure were observed in 17.5% ( = 7) of patients: 22.2% ( = 4) with ruptured and 13.6% ( = 3) with unruptured aneurysms.
Endovascular treatment of MCA aneurysms is feasible, and our results are convergent with other studies. Ruptured MCA aneurysms may be treated endovascularly with similar effects as unruptured MCA aneurysms. The complication rate of such treatment is low.
大脑中动脉(MCA)是颅内动脉瘤的第二常见发病部位。传统上,此类动脉瘤通过显微手术夹闭进行治疗,但随着新技术和设备的发展,血管内栓塞治疗的重要性日益增加。本研究的目的是总结我科六年来在大脑中动脉动脉瘤血管内治疗方面的经验。
本研究纳入了在单一中心接受治疗的40例患有41个大脑中动脉动脉瘤的患者。收集了患者的合并症、动脉瘤形态及治疗过程等数据,特别关注并发症情况。
男性与女性、破裂动脉瘤与未破裂动脉瘤在动脉瘤形态方面无统计学显著差异。本研究分析的所有疾病均与蛛网膜下腔出血(SAH)风险显著增加无关。与破裂动脉瘤相比,未破裂动脉瘤采用支架辅助弹簧圈栓塞治疗的频率显著更高(30.4% 对5.6%,P = 0.0388),而破裂动脉瘤单独采用弹簧圈栓塞治疗的频率更高(77.8% 对34.8%,P = 0.0062)。初始治疗疗程结束后,63.4%(n = 26)的患者在Raymond-Roy闭塞分级中为I级,22%(n = 9)为II级,14.6%(n = 6)为III级。17.5%(n = 7)的患者出现了手术并发症:破裂动脉瘤患者中的发生率为22.2%(n = 4),未破裂动脉瘤患者中的发生率为13.6%(n = 3)。
大脑中动脉动脉瘤的血管内治疗是可行的,我们的结果与其他研究一致。破裂的大脑中动脉动脉瘤可通过血管内治疗,效果与未破裂的大脑中动脉动脉瘤相似。此类治疗的并发症发生率较低。