Rochlin Danielle H, Mittermiller Paul A, Menard Robert M
Division of Plastic Surgery, Stanford University School of Medicine, Stanford, Calif.
Northern California Kaiser Permanente Regional Craniofacial Clinic, Department of Plastic Surgery, Kaiser Permanente Santa Clara, Santa Clara, Calif.
Plast Reconstr Surg Glob Open. 2021 Jan 22;9(1):e3368. doi: 10.1097/GOX.0000000000003368. eCollection 2021 Jan.
The fate of the excised synostotic suture in craniosynostosis remains relatively understudied. The purpose of this report is to describe a case of neosagittal suture formation following endoscopic excision of a pathology-proven synostotic suture, with CT demonstration of complete reossification in the areas adjacent to the neosagittal suture. We additionally review the existing literature on neosuture formation that has been published over the past 50 years. We conclude that continued investigation is warranted, both through histological comparison of normal and neosutures and through studies to determine clinical risk factors, as this may improve our understanding of the underlying mechanism of pathologic premature suture fusion in craniosynostosis.
在颅缝早闭中,切除的融合骨缝的转归相对研究较少。本报告的目的是描述1例经病理证实的融合骨缝在内镜切除术后出现新矢状缝形成的病例,并通过CT显示新矢状缝相邻区域完全重新骨化。我们还回顾了过去50年发表的关于新骨缝形成的现有文献。我们得出结论,有必要通过对正常骨缝和新骨缝进行组织学比较以及通过研究确定临床风险因素来继续开展研究,因为这可能会增进我们对颅缝早闭中病理性过早骨缝融合潜在机制的理解。