纳米医学中的“文件抽屉问题”。

The File Drawer Problem in Nanomedicine.

机构信息

Department of Radiology and Precision Health Program, Michigan State University, East Lansing, MI, USA.

Department of Biological Sciences, Lehigh University, Bethlehem, PA, USA.

出版信息

Trends Biotechnol. 2021 May;39(5):425-427. doi: 10.1016/j.tibtech.2021.01.009. Epub 2021 Feb 8.

DOI:10.1016/j.tibtech.2021.01.009

PMID:33568314

Abstract

The role of the 'file drawer' problem in nanomedicine, which partly drives the current limited clinical success of therapeutic nanoparticles, has been poorly investigated. We propose an integrated functioning of all stakeholders as the only effective way to address the file drawer problem in an efficient and timely manner.

摘要

“文件抽屉”问题在纳米医学中的作用部分导致了治疗性纳米粒子目前有限的临床成功，而这一问题尚未得到充分研究。我们提出所有利益相关者的综合作用是及时有效地解决“文件抽屉”问题的唯一有效途径。