Kamisawa T, Tabata I, Isawa T, Egawa N, Tajima T, Okamoto A, Kawaguchi K, Fukayama M, Takizawa T, Koike M
Dept. of Internal Medicine, Tokyo Metropolitan Komagome Hospital.
Gan No Rinsho. 1988 Mar;34(3):356-60.
A case of a non-jaundiced ampullary carcinoma with a unique tumor spread is reported. A 3.2 X 1.0 cm-sized tumor at the ampulla of Vater was resected in a 64-year-old female. The primary focus of the well differentiated adenocarcinoma was confined to the intraampullary common channel, but the most of the tumor consisted of lymphatic permeation. A wide spread lymphogenous metastases had been noticed at operation, and the patient died nine months thereafter from metastases of the brain. The mechanism which prevented jaundice from developing in this case might be due to the unique way in which this tumor spread, without obstruction via the lymphatic space and only stenosing the bile duct.
报告了一例具有独特肿瘤扩散方式的无黄疸型壶腹癌病例。一名64岁女性患者,其位于 Vater 壶腹的一个3.2×1.0厘米大小的肿瘤被切除。高分化腺癌的原发灶局限于壶腹内的共同通道,但大部分肿瘤由淋巴浸润组成。手术中发现广泛的淋巴源性转移,患者此后九个月死于脑转移。该病例中阻止黄疸发生的机制可能是由于肿瘤独特的扩散方式,即通过淋巴间隙无阻塞且仅使胆管狭窄。