Department of Women's and Children's Health, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Dipartimento per la salute della Donna e del Bambino e della Salute Pubblica, Rome, Italy.
Università Cattolica del Sacro Cuore, Rome, Italy.
Ann Surg Oncol. 2021 Oct;28(11):6721-6722. doi: 10.1245/s10434-021-09651-2. Epub 2021 Feb 14.
Ovarian cancer is the most lethal of all gynecologic cancers. Primary debulking surgery (PDS) with achievement of no residual tumor (RT, 0) still is the recommended treatment, and the one with the greatest prognostic impact. Given the usual disease spread, several surgical procedures often are needed, and one of the most frequent is rectosigmoid resection. Anastomotic leak is the most feared complication. Other common complications are persistent urinary, defecatory, and sexual dysfunction due to autonomic nervous system injuries during surgery. Even if mesorectal resection is not deemed part of the treatment paradigm for advanced ovarian cancer (AOC), total mesorectal excision (TME) is the most common surgical technique used. However, for selected cases, with detection of no lymphadenopathies at the origin of the of the inferior mesenteric artery and a favorable ratio between the length of the left colon and the extent of the bowel carcinomatosis, a mesorectal-sparing resection with the preservation of the superior rectal artery and the mesorectal tissue should be pursued. This report presents the case of a 54-year-old woman with a diagnosis of FIGO stage 3C AOC who underwent PDS. The video (video 1) provides a step-by-step description of the surgical technique adopted for colorectal resection with mesorectal-sparing technique. Rectosigmoid mesorectal-sparing resection is feasible and could be a viable option for selected cases of AOC, maximizing the blood supply to colorectal anastomosis while minimizing the risk of both anastomotic leak and pelvic autonomic nervous system dysfunction..
卵巢癌是所有妇科癌症中最致命的。初次肿瘤细胞减灭术(PDS)达到无残余肿瘤(RT,0)仍然是推荐的治疗方法,也是对预后影响最大的方法。鉴于通常的疾病扩散,通常需要进行几次手术,其中最常见的一种是直肠乙状结肠切除术。吻合口漏是最可怕的并发症。其他常见的并发症包括由于手术过程中自主神经系统损伤导致的持续性尿、排便和性功能障碍。即使直肠系膜切除术不被认为是晚期卵巢癌(AOC)治疗模式的一部分,全直肠系膜切除术(TME)仍然是最常用的手术技术。然而,对于某些选定的病例,如果在下肠系膜动脉起始处未发现淋巴结病,并且左结肠的长度与结直肠癌转移的程度之间存在有利的比例,则应采用保留直肠上动脉和直肠系膜组织的直肠系膜保留切除术。本报告介绍了一例 54 岁女性,诊断为国际妇产科联合会(FIGO)分期 3C 期 AOC,行 PDS 治疗。视频(视频 1)提供了采用直肠系膜保留技术进行结直肠切除术的手术技术的逐步描述。直肠乙状结肠系膜保留切除术是可行的,对于某些选定的 AOC 病例可能是一种可行的选择,在最大化结直肠吻合的血液供应的同时,最小化吻合口漏和骨盆自主神经系统功能障碍的风险。