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门诊髋关节和膝关节置换术的安全性与有效性:一项系统评价及荟萃分析

Safety and efficacy of outpatient hip and knee arthroplasty: a systematic review with meta-analysis.

作者信息

Bemelmans Y F L, Keulen M H F, Heymans M, van Haaren E H, Boonen B, Schotanus M G M

机构信息

Department of Orthopaedic Surgery, Zuyderland Medical Center, dr. H vd Hoffplein 1, 6162 AG, Sittard-Geleen, The Netherlands.

Library, Zuyderland Medical Center, Sittard-Geleen, The Netherlands.

出版信息

Arch Orthop Trauma Surg. 2022 Aug;142(8):1775-1791. doi: 10.1007/s00402-021-03811-5. Epub 2021 Feb 15.

Abstract

INTRODUCTION

This systematic review aimed to assess the safety and efficacy of outpatient joint arthroplasty (OJA) pathways compared to inpatient pathways.

MATERIALS AND METHODS

An electronic literature search was conducted to identify eligible studies. Studies comparing OJA with inpatient pathways-following hip and/or (partial) knee arthroplasty-were included. Included studies were assigned-based on OJA definition-to one of the following two groups: (1) outpatient surgery (OS); outpatient defined as discharge on the same day as surgery; and (2) semi-outpatient surgery (SOS); outpatient defined as discharge within 24 h after surgery with or without an overnight stay. Methodological quality was assessed. Outcomes included (serious) adverse events ((S)AEs), readmissions, successful same-day discharge rates, patient-reported outcome measures (PROMs) and costs. Meta-analyses and subgroup analyses by type of arthroplasty were performed when deemed appropriate.

RESULTS

A total of 41 studies (OS = 26, SOS = 15) met the inclusion criteria. One RCT and 40 observational studies were included, with an overall risk-of-bias of moderate to high. Forty studies were included in the meta-analysis. Outpatients (both OS and SOS) were younger and had a lower BMI and ASA class compared to inpatients. Overall, no significant differences between outpatients and inpatients were found for overall complications and readmission rates, and improvement in PROMs. By type of arthroplasty, only THAs in OS pathways were associated with fewer AEs [OR = 0.55 (0.41-0.74)] compared to inpatient pathways. 92% of OS patients were discharged on the day of surgery. OJA resulted in an average cost reduction of $6.797,02.

CONCLUSION

OJA pathways are as safe and effective as inpatient pathways in selected populations, with a potential reduction of costs. Considerable risk of bias in the majority of studies emphasizes the need for further research.

摘要

引言

本系统评价旨在评估门诊关节置换术(OJA)路径与住院路径相比的安全性和有效性。

材料与方法

进行电子文献检索以识别符合条件的研究。纳入比较髋关节和/或(部分)膝关节置换术后OJA与住院路径的研究。根据OJA定义,将纳入的研究分为以下两组之一:(1)门诊手术(OS);门诊定义为手术当天出院;(2)半门诊手术(SOS);门诊定义为术后24小时内出院,有无过夜住院均可。评估方法学质量。结果包括(严重)不良事件((S)AEs)、再入院率、成功同日出院率、患者报告结局指标(PROMs)和费用。在认为适当时,按关节置换类型进行荟萃分析和亚组分析。

结果

共有41项研究(OS = 26,SOS = 15)符合纳入标准。纳入1项随机对照试验和40项观察性研究,总体偏倚风险为中度至高。40项研究纳入荟萃分析。与住院患者相比,门诊患者(OS和SOS)更年轻,BMI和ASA分级更低。总体而言,门诊患者和住院患者在总体并发症、再入院率和PROMs改善方面未发现显著差异。按关节置换类型,与住院路径相比,仅OS路径中的全髋关节置换术(THA)不良事件较少[比值比(OR)= 0.55(0.41 - 0.74)]。92%的OS患者在手术当天出院。OJA平均成本降低6797.02美元。

结论

在特定人群中,OJA路径与住院路径一样安全有效,且有可能降低成本。大多数研究中存在相当大的偏倚风险,强调需要进一步研究。

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